Evidence map›Paper›PMID 34873478›Full record

ArticleAmerican journal of cancer research2021

Whole-exome sequencing,

Concha López-Ginés, Lisandra Muñoz-Hidalgo, Teresa San-Miguel, Javier Megías, Juan Carlos Triviño, Silvia Calabuig, Pedro Roldán, Miguel Cerdá-Nicolás, Daniel Monleón

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Molecular Biomarkers in Glioblastoma: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2022
    Pooled it
  2. Next-Generation Sequencing Reveals a Diagnostic and Prognostic Role of theInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Concha López-GinésDepartament of Pathology, University of Valencia Valencia, Spain.
Lisandra Muñoz-HidalgoHealth Research Institute INCLIVA Valencia, Spain.
Teresa San-MiguelDepartament of Pathology, University of Valencia Valencia, Spain.
Javier MegíasDepartament of Pathology, University of Valencia Valencia, Spain.
Juan Carlos TriviñoSistemas Genómicos Inc. Valencia, Spain.
Silvia CalabuigDepartament of Pathology, University of Valencia Valencia, Spain.
Pedro RoldánDepartment of Neurosurgery, University Clinical Hospital Valencia Valencia, Spain.
Miguel Cerdá-NicolásDepartament of Pathology, University of Valencia Valencia, Spain.
Daniel MonleónDepartament of Pathology, University of Valencia Valencia, Spain.
Universitat de València · ESINCLIVA Health Research Institute · ESSistemas Genómicos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. This cancer shows rapid, highly infiltrative growth, that invades individually or in small groups the surrounding tissue. The aggressive tumor biology of GBM has devastating consequences with a median survival of 15 months. GBM often has Epidermal Growth Factor Receptor (

Indexed as

EGFR amplificationFISHGlioblastoma (GBM)infiltration patternssomatic mutationwhole exome sequencing

Identifiers

PMID34873478
PMCPMC8640814
OpenAlexW4206889508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.