ArticleCommunications biology2021
Diversification of ergot alkaloids and heritable fungal symbionts in morning glories.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Monitoring and Managing of Ergot Alkaloids in Cereal Grains: A Comprehensive Analysis of Analytical Challenges, Sampling Uncertainty, and Processing for Food Safety.Comprehensive reviews in food science and food safety · 2026Review
- Unveiling nonribosomal peptide synthetases from the ergot fungusActa pharmaceutica Sinica. B · 2025Article
- Article
- Gene editing of the thioester reductase step in the biosynthesis of lysergic acid amides.PloS one · 2025Article
- Exploring the diversity of microbes and natural products from fungus-growing termite tripartite symbiosis.Engineering microbiology · 2024Review
- Derivation of the multiply-branched ergot alkaloid pathway of fungi.Microbial biotechnology · 2023Review
- Success stories of natural product-derived compounds from plants as multidrug resistance modulators in microorganisms.RSC advances · 2023Review
- The long road of functional recruitment-The evolution of a gene duplicate to pyrrolizidine alkaloid biosynthesis in the morning glories (Convolvulaceae).Plant direct · 2022Article
- Untargeted Metabolomics Sheds Light on the Diversity of Major Classes of Secondary Metabolites in the Malpighiaceae Botanical Family.Frontiers in plant science · 2022Article
- A Bird's Eye View of the Systematics of Convolvulaceae: Novel Insights From Nuclear Genomic Data.Frontiers in plant science · 2022Article
- Phylogenetic Patterns of Swainsonine Presence in Morning Glories.Frontiers in microbiology · 2022Article
- Diversification of ergot alkaloids and heritable fungal symbionts in morning glories.Communications biology · 2021Article
- A new species ofMycologiaArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heritable microorganisms play critical roles in life cycles of many macro-organisms but their prevalence and functional roles are unknown for most plants. Bioactive ergot alkaloids produced by heritable Periglandula fungi occur in some morning glories (Convolvulaceae), similar to ergot alkaloids in grasses infected with related fungi. Ergot alkaloids have been of longstanding interest given their toxic effects, psychoactive properties, and medical applications. Here we show that ergot alkaloids are concentrated in four morning glory clades exhibiting differences in alkaloid profiles and are more prevalent in species with larger seeds than those with smaller seeds. Further, we found a phylogenetically-independent, positive correlation between seed mass and alkaloid concentrations in symbiotic species. Our findings suggest that heritable symbiosis has diversified among particular clades by vertical transmission through seeds combined with host speciation, and that ergot alkaloids are particularly beneficial to species with larger seeds. Our results are consistent with the defensive symbiosis hypothesis where bioactive ergot alkaloids from Periglandula symbionts protect seeds and seedlings from natural enemies, and provide a framework for exploring microbial chemistry in other plant-microbe interactions.
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Registered trials
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