ArticleTranslational psychiatry2021
Relationship between sensory characteristics and cortical thickness/volume in autism spectrum disorders.
Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Gray matter covariations in autism: out-of-sample replication using the ENIGMA autism cohort.Molecular autism · 2024Pooled it
- Ethical Complexities and Concerns Surrounding Magnetic Resonance Imaging and the Open-Access Scientific Framework in Autism Research.Autism in adulthood · 2026Article
- Autism and Cortical Thickness Deviation From Neurotypical Controls: Evidence for a Spatial Association With Serotonin Receptors.Autism research : official journal of the International Society for Autism Research · 2026Article
- Self-Report of Restricted Repetitive Behaviors in Autistic Adults: A Systematic Review.Autism in adulthood · 2026Article
- Dissecting the heterogeneity of autism spectrum disorder with sensory behavior, brain, and epigenetic factors.Translational psychiatry · 2025Article
- Sensory seeking and its influence on sustained attention performance in adult males with Autism Spectrum Condition.Scientific reports · 2025Article
- Loss-of-function variant in spermidine/spermine N1-acetyl transferase like 1 (SATL1) gene as an underlying cause of autism spectrum disorder.Scientific reports · 2024Article
- Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder.Frontiers in psychiatry · 2024Review
- Article
- Vasotocin receptor gene genotypes moderate the relationship between cortical thickness and sensory processing.Translational psychiatry · 2023Article
- Article
- Multi-site harmonization of MRI data uncovers machine-learning discrimination capability in barely separable populations: An example from the ABIDE dataset.NeuroImage. Clinical · 2022Article
- Modulation of the thermosensory system by oxytocin.Frontiers in molecular neuroscience · 2022Review
- Morphological and Functional Changes of Cerebral Cortex in Autism Spectrum Disorder.Innovations in clinical neuroscienceReview
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals with autism spectrum disorders (ASDs) exhibit atypical sensory characteristics, impaired social skills, deficits in verbal and nonverbal communication, and restricted and repetitive behaviors. The relationship between sensory characteristics and brain morphological changes in ASD remains unclear. In this study, we investigated the association between brain morphological changes and sensory characteristics in individuals with ASD using brain image analysis and a sensory profile test. Forty-three adults with ASD and 84 adults with typical development underwent brain image analysis using FreeSurfer. The brain cortex was divided into 64 regions, and the cortical thickness and volume of the limbic system were calculated. The sensory characteristics of the participants were evaluated using the Adolescent/Adult Sensory Profile (AASP). Correlation analysis was performed for cortical thickness, limbic area volume, and AASP scores. In the ASD group, there was a significant positive correlation between visual sensory sensitivity scores and the right lingual cortical thickness (r = 0.500). There were also significant negative correlations between visual sensation avoiding scores and the right lateral orbitofrontal cortical thickness (r = -0.513), taste/smell sensation avoiding scores and the right hippocampal volume (r = -0.510), and taste/smell sensation avoiding scores and the left hippocampal volume (r = -0.540). The study identified associations among the lingual cortical thickness, lateral orbitofrontal cortical thickness, and hippocampal volume and sensory characteristics. These findings suggest that brain morphological changes may trigger sensory symptoms in adults with ASD.
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Registered trials
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