Evidence map›Paper›PMID 34872985›Full record

Observational studyJournal of neurointerventional surgery2022

Evaluation of direct-to-angiography suite (DTAS) and conventional clinical pathways in stroke care: a simulation study.

Mehrad Bastani, Timothy G White, Gabriela Martinez, Joseph Ohara, Kinpritma Sangha, Michele Gribko, Jeffrey M Katz, Henry H Woo, Artem T Boltyenkov, Jason Wang and 3 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of neurointerventional surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Mehrad BastaniRadiology, Northwell Health Feinstein Institutes for Medical Research, Manhasset, New York, USA mbastani@northwell.edu.ORCID http://orcid.org/0000-0001-9571-9488
Timothy G WhiteNeurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, New York, USA.ORCID http://orcid.org/0000-0002-3604-4334
Gabriela MartinezSiemens Healthcare USA, Manhasset, New York, USA.
Joseph OharaNorthwell Health, New Hyde Park, New York, USA.
Kinpritma SanghaSiemens Healthineers AG, Malvern, Pennsylvania, USA.
Michele GribkoNorth Shore University Hospital, Manhasset, New York, USA.
Jeffrey M KatzNeurology, North Shore University Hospital at Manhasset, Manhasset, New York, USA.
Henry H WooNeurosurgery, Northwell Health, Manhasset, New York, USA.
Artem T BoltyenkovSiemens Healthineers USA, Malvern, Pennsylvania, USA.
Jason WangDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
Elizabeth RulaHarvey L Neiman Health Policy Institute, Reston, Virginia, USA.
Jason J NaidichRadiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
Pina C SanelliHofstra Northwell School of Medicine at Hofstra University, Hempstead, New York, USA.
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell · USNorthwell Health · USSiemens Healthcare (United States) · USNorth Shore University Hospital · USHarvey L. Neiman Health Policy Institute · USHofstra University · US

Funding

Comparative Effectiveness of Imaging Strategies in Acute Ischemic Stroke Based on Patient Profiles - Resubmission - 1R56NS114275 · NINDS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SANELLI, PINA CHRISTINE · 2020 to 2020
$628k
NINDS NIH HHS R56 NS114275
6 · The paper itself

Abstract

backgroundRapid time to reperfusion is essential to minimize morbidity and mortality in acute ischemic stroke due to large vessel occlusion (LVO). We aimed to evaluate the workflow times when utilizing a direct-to-angiography suite (DTAS) pathway for patients with suspected stroke presenting at a comprehensive stroke center compared with a conventional CT pathway.

methodsWe developed a discrete-event simulation (DES) model to evaluate DTAS workflow timelines compared with a conventional CT pathway, varying the admission NIHSS score treatment eligibility criteria. Model parameters were estimated based on 2 year observational data from our institution. Sensitivity analyses of simulation parameters were performed to assess the impact of patient volume and baseline utilization of angiography suites on workflow times utilizing DTAS.

resultsSimulation modeling of stroke patients (SimStroke) demonstrated door-to-reperfusion time savings of 0.2-3.5 min (p=0.05) for a range of DTAS eligibility criteria (ie, last known well to arrival <6 hours and National Institutes of Health Stroke Scale ≥6-11), when compared with the conventional stroke care pathway. Sensitivity analyses revealed that DTAS time savings is highly dependent on baseline utilization of angiography suites.

conclusionsThe results of the SimStroke model showed comparable time intervals for door-to-reperfusion for DTAS compared with a conventional stroke care pathway. However, the DTAS pathway was very sensitive to baseline angiography suite utilization, with even a 10% increase eliminating the advantages of DTAS compared with the conventional pathway. Given the minimal time savings modeled here, further investigation of implementing the DTAS pathway in clinical care is warranted.

Indexed as

Brain IschemiaIschemic StrokeStrokeAngiographyCritical PathwaysHumansPatient SimulationThrombectomyTreatment OutcomeCT angiographystatisticsstrokethrombectomy

Identifiers

PMID34872985
PMCPMC9167885
OpenAlexW4200290674

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.