Evidence map›Paper›PMID 34872938›Full record

ArticleeNeuro

FKBP51 in the Oval Bed Nucleus of the Stria Terminalis Regulates Anxiety-Like Behavior.

Clara Engelhardt, Fiona Tang, Radwa Elkhateib, Joeri Bordes, Lea Maria Brix, Lotte van Doeselaar, Alexander S Häusl, Max L Pöhlmann, Karla Schraut, Huanqing Yang and 3 more

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Neurobiology of stress · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Deep phenotyping reveals CRH and FKBP51-dependent behavioral profiles following chronic social stress exposure in male mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Clara EngelhardtResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Fiona TangResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Radwa ElkhateibResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Joeri BordesResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Lea Maria BrixResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.ORCID 0000-0002-3655-4385
Lotte van DoeselaarResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Alexander S HäuslResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Max L PöhlmannResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Karla SchrautResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Huanqing YangResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Alon ChenDepartment of Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Jan M DeussingResearch Group Molecular Neurogenetics, Max Planck Institute of Psychiatry, Munich 80804, Germany.
Mathias V SchmidtResearch Group Neurobiology of Stress Resilience, Max Planck Institute of Psychiatry, Munich 80804, Germany mschmidt@psych.mpg.de.
Max Planck Institute of Neurobiology · DEMax Planck Institute of Psychiatry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cochaperone FKBP51, encoded by the

Indexed as

NeuropeptidesSeptal NucleiAnimalsAnxietyHypothalamo-Hypophyseal SystemMicePituitary-Adrenal SystemTacrolimus Binding Protein 5Tacrolimus Binding ProteinsNeuropeptidesTacrolimus Binding Protein 5Tacrolimus Binding ProteinsanxietyBNSTFKBP5mousestress

Identifiers

PMID34872938
PMCPMC8687485
OpenAlexW4200090803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.