Evidence map›Paper›PMID 34872726›Full record

ArticleThe Journal of investigative dermatology2022

BRAF Inhibitors in Melanoma Management: When Friends Become Foes.

Gagan Chhabra, Nihal Ahmad

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of investigative dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gagan ChhabraDepartment of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nihal AhmadDepartment of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA; William S. Middleton VA Medical Center, Madison, Wisconsin, USA. Electronic address: nahmad@dermatology.wisc.edu.
University of Wisconsin–Madison · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Role of polo like kinase 4 in melanomagenesis and melanoma progressionI01BX004221 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI AHMAD, NIHAL · 2019 to 2022
–
Role of SIRT3 in melanoma development and progressionI01CX001441 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI AHMAD, NIHAL · 2017 to 2022
–
Role of sirtuin 6 in melanoma development and progressionI01CX002210 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI Nihal Ahmad · 2022 to 2026
–
BLR&D Research Career Scientist Award ApplicationIK6BX003780 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI AHMAD, NIHAL · 2017 to 2021
–
BLRD VA I01 BX004221BLRD VA IK6 BX003780CSRD VA I01 CX001441CSRD VA I01 CX002210NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

The BRAF inhibitor (BRAFi) vemurafenib improves survival of patients with melanoma with BRAF

Indexed as

MelanomaProto-Oncogene Proteins B-rafAnimalsCell Line, TumorDrug Resistance, NeoplasmFriendsHumansIndolesMiceMutationProtein Kinase InhibitorsSulfonamidesVemurafenibBRAF protein, humanIndolesProtein Kinase InhibitorsProto-Oncogene Proteins B-rafSulfonamidesVemurafenib

Identifiers

PMID34872726
PMCPMC9199497
OpenAlexW4200604644

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.