Trial reportPsychological medicine2022
Results of the first randomized controlled trial of integrated cognitive-behavioral therapy for eating disorders and posttraumatic stress disorder.
Trial report in Psychological medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 34 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 5 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Prevalence, Aetiology and Treatment of Comorbid Post-traumatic Stress Disorder and Eating Disorders in Children and Young People: A Systematic Review.Clinical child and family psychology review · 2025Pooled it
- Psychological Treatment of Co-Occurring Trauma History, Posttraumatic Stress Disorder, and Eating Disorders: A Systematic Review of Clinical Outcomes.European eating disorders review : the journal of the Eating Disorders Association · 2025Pooled it
- Biological treatments for co-occurring eating disorders and psychological trauma: a systematic review.Frontiers in psychiatry · 2025Pooled it
- A Systematic Review of the Effect of PTSD and Trauma on Treatment Outcomes for Eating Disorders.Trauma, violence & abuse · 2024Pooled it
- Posttraumatic stress disorder, traumatic events, and longitudinal eating disorder treatment outcomes: A systematic review.The International journal of eating disorders · 2023Pooled it
- Eye Movement Desensitization and Reprocessing with and without Dialectical Behavior Therapy for Posttraumatic Stress Disorder and Comorbid Borderline Personality Disorder Symptoms: A Randomized Controlled Trial.Psychotherapy and psychosomatics · 2025Trial
- Impact of three variants of prolonged exposure therapy on comorbid diagnoses in patients with childhood abuse-related PTSD.Cognitive behaviour therapy · 2024Trial
- Therapists' Attitudes and Exclusion Criteria for Prolonged Exposure and EMDR in Patients With Eating Disorders and PTSD.European eating disorders review : the journal of the Eating Disorders Association · 2026Article
- A unified theory of restrictive and addictive eating: a life course model integrating generational transmission, neurodevelopmental risk, and ultra-processed food use disorder-a theoretical review.Journal of eating disorders · 2026Review
- I am in the passenger seat of my own body: a qualitative interview study of the relationship between binge eating and concurrent problematic alcohol use.Journal of eating disorders · 2026Article
- Eating disorder symptoms and corresponding evidence-based treatments: a narrative review.Journal of eating disorders · 2026Review
- Childhood Sexual Abuse and Its Association with Clinical and Psychological Features in Patients with Eating Disorders in China.Neuropsychiatric disease and treatment · 2026Article
- Exploring MDMA assisted therapy in eating disorders: mechanisms, clinical evidence, and future directions.Journal of eating disorders · 2025Review
- From shared mechanisms to treatment gaps: a review of the comorbidity between eating disorders and PTSD.Journal of eating disorders · 2025Review
- PTSD, complex PTSD and the dissociative subtype of PTSD in patients with eating disorders.Journal of eating disorders · 2025Article
- Exploring the Additive Benefit of PTSD Treatment on Eating Disorder Outcomes for Those with Co-Occurring PTSD.Behavioral sciences (Basel, Switzerland) · 2025Article
- Written Exposure Therapy and Dialectical Behavior Therapy Skills Training as a Novel Integrated Intervention for Women With Co-Occurring PTSD and Eating Disorders: Two Case Studies.Cognitive and behavioral practice · 2025Article
- Understanding Personalized Dynamics in Eating Disorders: A Dynamic Time Warp Analysis.The International journal of eating disorders · 2025Article
- Overcoming Implementation Barriers of Concurrent Treatment for Eating Disorders and Posttraumatic Stress Disorder: Two Novel and Feasible Approaches.Behavioral sciences (Basel, Switzerland) · 2025Article
- Identifying candidate mechanisms of comorbidity in disordered eating and posttraumatic stress disorder symptoms among U.S. veterans: A network analytic approach.Psychological trauma : theory, research, practice and policy · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEating disorders (EDs) and posttraumatic stress disorder (PTSD) frequently co-occur and can share a functional relationship. The primary aim of this initial randomized controlled trial was to determine whether integrated cognitive-behavioral therapy (CBT) for co-occurring ED-PTSD was superior to standard CBT for ED in improving PTSD symptoms. Intervention safety and desirability, as well as the relative efficacy of the treatments in improving anxiety, depression, and ED symptomatology, were also examined.
methodsFollowing a course of intensive ED treatment, individuals with ED-PTSD were recruited to participate and randomized to integrated CBT for ED-PTSD or standard CBT for ED. The sample consisted of 42 individuals with a range of ED diagnoses. Outcomes were assessed at end-of-treatment, 3-, and 6-month follow-up using interview and self-report measures.
resultsMixed models revealed significant interactions of time and therapy condition on clinician-rated and self-reported PTSD symptom severity favoring Integrated CBT for ED-PTSD. Both treatments were associated with statistically significant improvements in PTSD, anxiety, and depression. Improvements were maintained at 3- and 6-month follow-up. There was good safety with both interventions, and satisfaction with both treatments was high. However, there was a stronger preference for integrated treatment.
conclusionsIntegrating CBTs for PTSD and ED following intensive ED treatment is safe, desirable, and efficacious for improving PTSD symptoms. Future studies with larger sample sizes are needed to determine whether Integrated CBT for ED-PTSD provides benefits over standard CBT for ED with respect to ED outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.