Evidence map›Paper›PMID 34872549›Full record

ArticleBMC pulmonary medicine2021

Predicting feeding-tube dependence in patients following endotracheal extubation: a two-item swallowing screen.

Shu-Fen Siao, Wen-Hsuan Tseng, Tyng-Guey Wang, Yu-Chung Wei, Tzu-Yu Hsiao, Shih-Chi Ku, Cheryl Chia-Hui Chen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03284892 (Screen and Intervene), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03284892 nacompletednot on this map

Screen and Intervene: A Diagnostic Accuracy Study and A Randomized, Open-label, Controlled Trial for Postextubation Dysphagia

TypeinterventionalSponsorNational Taiwan University HospitalRan2017 to 2020Enrolled145ConditionsOropharyngeal Dysphagia, Swallowing Disorder, Randomized Controlled Trial, Endotracheal IntubationArmsSOC program
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shu-Fen SiaoDepartment of Nursing, National Taiwan University College of Medicine, Taipei, Taiwan R.O.C.
Wen-Hsuan TsengDepartment of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan R.O.C.
Tyng-Guey WangDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan R.O.C.
Yu-Chung WeiGraduate Institute of Statistics and Information Science, National Changhua University of Education, Changhua, Taiwan R.O.C.
Tzu-Yu HsiaoDepartment of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan R.O.C.
Shih-Chi KuDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, 7, Chung Shan S. Rd., Zhongzheng Dist., Taipei, 100, Taiwan R.O.C.. scku1015@gmail.com.
Cheryl Chia-Hui ChenDepartment of Nursing, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan R.O.C.
National Taiwan University Hospital · TWNational Changhua University of Education · TWNational Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo meet the surging demands for intubation and invasive ventilation as more COVID-19 patients begin their recovery, clinicians are challenged to find an ultra-brief and minimally invasive screen for postextubation dysphagia predicting feeding-tube dependence persisting for 72 h after extubation.

methodsThis study examined the predictive validity of a two-item swallowing screen on feeding-tube dependence over 72 h in patients following endotracheal extubation. Intensive-care-unit (ICU) patients (≥ 20 years) successfully extubated after ≥ 48 h endotracheal intubation were screened by trained nurses using the swallowing screen (comprising oral stereognosis and cough-reflex tests) 24 h postextubation. Feeding-tube dependence persisting for 72 h postextubation was abstracted from the medical record by an independent rater. To verify the results and cross-check whether the screen predicted penetration and/or aspiration during fiberoptic endoscopic evaluation of swallowing (FEES), participants agreeing to receive FEES were analyzed within 30 min of screening.

resultsThe results showed that 95/123 participants (77.2%) failed the screen, which predicted ICU patients' prolonged (> 72 h) feeding-tube dependence, yielding sensitivity of 0.83, specificity of 0.35, and accuracy of 0.68. Failed-screen participants had 2.96-fold higher odds of feeding-tube dependence (95% CI, 1.13-7.76). For the 38 participants receiving FEES, the swallowing screen had 0.89 sensitivity to detect feeding-tube dependence and 0.86 sensitivity to predict penetration/aspiration, although specificity had room for improvement (0.36 and 0.21, respectively).

conclusionThis ultra-brief swallowing screen is sufficiently sensitive to identify high-risk patients for feeding-tube dependence persisting over 72 h after extubation. Once identified, a further assessment and care are indicated to ensure the prompt return of patients' oral feeding.

trial registrationNCT03284892, registered on September 15, 2017.

Indexed as

Enteral NutritionAgedAirway ExtubationCOVID-19Critical CareDeglutition DisordersFemaleHumansIntubation, IntratrachealMaleMiddle AgedPredictive Value of TestsRisk FactorsTime FactorsDeglutitionDysphagiaEndotracheal intubationFeeding-tube dependenceIntensive care unitNutritional statusSwallowing

Identifiers

PMID34872549
PMCPMC8647059
OpenAlexW4200404706

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.