Evidence map›Paper›PMID 34872080›Full record

ReviewFetal diagnosis and therapy2022

Methods for Monitoring Risk of Hypoxic Damage in Fetal and Neonatal Brains: A Review.

Liaisan Uzianbaeva, Yan Yan, Tanaya Joshi, Nina Yin, Chaur-Dong Hsu, Edgar Hernandez-Andrade, Mohammad Mehrmohammadi

Open access · bronzeAbstract readReview
In one paragraph

Review in Fetal diagnosis and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Magnetic resonance imaging of the monkey fetal brain in utero.Investigative magnetic resonance imaging · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Liaisan UzianbaevaDepartment of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
Yan YanDepartment of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
Tanaya JoshiDepartment of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
Nina YinDepartment of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
Chaur-Dong HsuDepartment of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Edgar Hernandez-AndradeDepartment of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Health Science Center, Houston, Texas, USA.
Mohammad MehrmohammadiDepartment of Biomedical Engineering, Wayne State University, Detroit, Michigan, USA.
Wayne State University · USNational Institutes of Health · USThe University of Texas Health Science Center at Houston · US

Funding

Molecular, Functional, and Microstructural Imaging of Cervical Remodeling BiomarkersR01EB030058 · NIBIB · WAYNE STATE UNIVERSITY · PI MEHRMOHAMMADI, MOHAMMAD · 2020 to 2023
$1.6M
NIBIB NIH HHS R01 EB030058
6 · The paper itself

Abstract

Fetal, perinatal, and neonatal asphyxia are vital health issues for the most vulnerable groups in human beings, including fetuses, newborns, and infants. Severe reduction in oxygen and blood supply to the fetal brain can cause hypoxic-ischemic encephalopathy (HIE), leading to long-term neurological disorders, including mental impairment and cerebral palsy. Such neurological disorders are major healthcare concerns. Therefore, there has been a continuous effort to develop clinically useful diagnostic tools for accurately and quantitatively measuring and monitoring blood and oxygen supply to the fetal and neonatal brain to avoid severe consequences of asphyxia HIE and neonatal encephalopathy. Major diagnostic technologies used for this purpose include fetal heart rate monitoring, fetus scalp blood sampling, ultrasound imaging, magnetic resonance imaging, X-ray computed tomography, and nuclear medicine. In addition, given the limitations and shortcomings of traditional diagnostic methods, emerging technologies such as near-infrared spectroscopy and photoacoustic imaging have also been introduced as stand-alone or complementary solutions to address this critical gap in fetal and neonatal care. This review provides a thorough overview of the traditional and emerging technologies for monitoring fetal and neonatal brain oxygenation status and describes their clinical utility, performance, advantages, and disadvantages.

Indexed as

Asphyxia NeonatorumHypoxia-Ischemia, BrainBrainFemaleFetusHumansHypoxiaInfantInfant, NewbornPregnancyBlood flowDiagnostic imagingFetal asphyxiaHypoxic-ischemic encephalopathyMagnetic resonance imagingNeonatal asphyxiaNeonatal encephalopathyOxygenationPhotoacoustic imagingUltrasoundX-ray computed tomography

Identifiers

PMID34872080
PMCPMC8983560
OpenAlexW4200028802

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.