Evidence map›Paper›PMID 34872055›Full record

ArticleThe American journal of tropical medicine and hygiene2021

Impact of Temperature and Rainfall on Typhoid/Paratyphoid Fever in Taizhou, China: Effect Estimation and Vulnerable Group Identification.

Qi Gao, Zhidong Liu, Jianjun Xiang, Ying Zhang, Michael Xiaoliang Tong, Shuzi Wang, Yiwen Zhang, Qiyong Liu, Baofa Jiang, Peng Bi

Open access · greenAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Risk Factors for Typhoid Fever: Systematic Review.JMIR public health and surveillance · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Typhoid fever.Nature reviews. Disease primers · 2023
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Qi GaoDepartment of Epidemiology and Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, People's Republic of China.
Zhidong LiuDepartment of Personnel, Qilu Hospital of Shandong University, Jinan, Shandong Province, People's Republic of China.
Jianjun XiangSchool of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.
Ying ZhangSchool of Public Health, China Studies Centre, The University of Sydney, New South Wales, Australia.
Michael Xiaoliang TongSchool of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.
Shuzi WangShandong Center for Disease Control and Prevention, Jinan, Shandong Province, People's Republic of China.
Yiwen ZhangYunnan Center for Disease Control and Prevention, Kunming, Yunnan Province, People's Republic of China.
Qiyong LiuShandong University Climate Change and Health Center, Jinan, Shandong Province, People's Republic of China.
Baofa JiangDepartment of Epidemiology and Biostatistics, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province, People's Republic of China.
Peng BiSchool of Public Health, The University of Adelaide, Adelaide, South Australia, Australia.
University of Adelaide · AUShandong University · CNYunnan Center for Disease Control And Prevention · CNNational Institute for Communicable Disease Control and Prevention · CNQilu Hospital of Shandong University · CNShandong Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of temperature and rainfall on the occurrence of typhoid/paratyphoid fever are not fully understood. This study aimed to characterize the effect of daily ambient temperature and total rainfall on the incidence of typhoid/paratyphoid in a sub-tropical climate city of China and to identify the vulnerable groups for disease prevention. Daily notified typhoid/paratyphoid fever cases and meteorological data for Taizhou from 2005 to 2013 were extracted from the National Notifiable Disease Surveillance System and the Meteorological Data Sharing Service System, respectively. Distributed lag nonlinear model was used to quantify the association between daily mean temperature, total rainfall, and typhoid/paratyphoid fever. Subgroup analyses by gender, age, and occupation were conducted to identify the vulnerable groups. A total of 625 typhoid fever cases and 1,353 paratyphoid fever cases were reported during the study period. An increased risk of typhoid fever was detected with the increase of temperature (Each 2°C rise resulted in 6%, 95% [confidence interval] CI: 2-10% increase in typhoid cases), while the increased risk was associated with the higher temperature for paratyphoid (the highest cumulative risk of temperature was 33.40 [95% CI: 12.23-91.19] at 33°C). After the onset of mild precipitation, the relative risk of typhoid fever increased in a short-lasting and with a 13-26 days delay, and the risk was no significant after the continuous increase of precipitation (the highest cumulative risk of rainfall was 24.96 [95% CI: 4.54-87.21] at 100 mm). Whereas the risk of paratyphoid fever was immediate and long lasting, and increase rapidly with the increase of rainfall (each 100 mm increase was associated with 26% increase in paratyphoid fever cases). Significant temperature-typhoid/paratyphoid fever and rainfall-typhoid/paratyphoid fever associations were found in both genders and those aged 0-4 years old, 15-60 years old, farmers, and children. Characterized with a lagged, nonlinear, and cumulative effect, high temperature and rainfall could increase the risk of typhoid/paratyphoid fever in regions with a subtropical climate. Public health interventions such as early warning and community health education should be taken to prevent the increased risk of typhoid/paratyphoid fever, especially for the vulnerable groups.

Indexed as

RainTemperatureAdolescentAdultChildChild, PreschoolChinaFarmersFemaleHumansIncidenceInfantInfant, NewbornMaleMiddle AgedParatyphoid Fever

Identifiers

PMID34872055
PMCPMC8832923
OpenAlexW4200313448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.