Evidence map›Paper›PMID 34871528›Full record

ArticleThe Journal of international medical research2021

Effect of glutathione S-transferase gene polymorphisms on semen quality in patients with idiopathic male infertility.

Hongyan Zhang, Jun He, Yili Zhao, Qifei Wu, Tiejun Zou, Jianhua Sun, Haitao Zhu, Xinyang Wang, Fa Sun, Junping Xing and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Association ofJournal of clinical medicine · 2023
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Hongyan ZhangThe Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Jun HeThe Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.ORCID https://orcid.org/0000-0002-0919-3094
Yili ZhaoThe Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Qifei WuThe First Affiliated Hospital of the Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China.ORCID https://orcid.org/0000-0002-7439-2831
Tiejun ZouPeople's Hospital of Shaanxi Province, Xi'an, Shaanxi, China.
Jianhua SunNorthwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Haitao ZhuNorthwest Women's and Children's Hospital, Xi'an, Shaanxi, China.
Xinyang WangThe First Affiliated Hospital of the Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Fa SunThe Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Junping XingThe First Affiliated Hospital of the Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Kaifa TangThe Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.ORCID https://orcid.org/0000-0001-7578-0679
Guiyang Medical University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNNorthwest Women's and Children's Hospital · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the relationship between glutathione S-transferase enzyme (

methodsSperm characteristics were measured using computer-assisted sperm analysis. The malondialdehyde (MDA), nitric oxide (NO), and total antioxidant capacity (TAC) activities were detected by spectroscopic analysis, and 8-hydroxy-2'-deoxyguanosine (8-OHdG) was detected by enzyme-linked immunosorbent assay.

resultsThis study included 246 idiopathic infertile men and 117 controls. The

conclusions

Indexed as

Infertility, MaleSemen AnalysisCase-Control StudiesGlutathione S-Transferase piGlutathione TransferaseHumansMalePolymorphism, GeneticSperm MotilityGlutathione S-Transferase piglutathione S-transferase T1Glutathione TransferaseGSTP1 protein, humangenetic variantGlutathione S-transferaseidiopathic male infertilityoxidative stresssemensperm

Identifiers

PMID34871528
PMCPMC8652180
OpenAlexW4200055421

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.