Evidence map›Paper›PMID 34871404›Full record

ArticleInteractive cardiovascular and thoracic surgery2022

The effect of aortic arch replacement on pulse wave velocity after surgery.

Daijiro Hori, Sho Kusadokoro, Makiko Naka Mieno, Tomonari Fujimori, Toshikazu Shimizu, Naoyuki Kimura, Atsushi Yamaguchi

Abstract read
In one paragraph

Article in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Daijiro HoriDepartment of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Sho KusadokoroDepartment of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.ORCID 0000-0002-4944-6092
Makiko Naka MienoDepartment of Medical Informatics, Center for Information, Jichi Medical University, Tochigi, Japan.
Tomonari FujimoriDepartment of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Toshikazu ShimizuDepartment of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Naoyuki KimuraDepartment of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.ORCID 0000-0003-2618-6934
Atsushi YamaguchiDepartment of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

Funding

JSPS KAKENHI JP21K16500Ministry of Education, Culture, Sports, Science and Technology
6 · The paper itself

Abstract

objectivesThe purpose of this study was to investigate the changes in pulse wave velocity (PWV) after aortic arch repair and to evaluate possible perioperative factors associated with an increase in PWV.

methodsEighty-nine patients with preoperative and postoperative PWV measurements who underwent surgical treatment for true aortic arch aneurysm were included in the study. The patients were treated by prosthetic graft replacement with or without the frozen elephant trunk technique or by hybrid surgery with a stent graft. Changes in PWV and perioperative factors were evaluated.

resultsFifty-one patients were treated by prosthetic graft replacement; 22 patients were treated with the frozen elephant trunk procedure; and 16 patients were treated by hybrid surgery. A significant increase in PWV was observed in patients undergoing surgical treatment for aortic arch aneurysm regardless of the types of operations performed (all treatments: before, 1797 ± 397.8 cm/s vs after, 2061 ± 600.4 cm/s, P < 0.001; graft replacement: before, 1769 ± 398.1 cm/s vs after, 1895 ± 459.0 cm/s, P = 0.004; frozen elephant trunk procedure: before, 1911 ± 461.9 cm/s vs after 2307 ± 826.9 cm/s, P = 0.005; hybrid surgery: before, 1732 ± 273.3 cm/s vs after, 2254 ± 484.6 cm/s, P < 0.001). Differences in PWV were largest in patients treated with hybrid surgery and lowest in those treated with graft replacement (P = 0.002). In univariate analysis, an increase in PWV was positively correlated with treatment length (r = 0.41; P < 0.001); the use of a postoperative beta blocker was associated with a smaller increase in postoperative PWV (with: 165.0 ± 371.92 cm/s vs without: 439.4 ± 530.38 cm/s, P = 0.005). Multivariate analysis suggested that treatment length (coefficient 3.31, 95% confidence interval 0.056-6.562, P = 0.046) and postoperative beta blocker (coefficient -220.08, 95% confidence interval -401.972 to -38.183, P = 0.018) were factors independently associated with changes in PWV.

conclusionsThere was a significant increase in PWV after aortic arch repair. Treatment length and use of postoperative beta blockers were factors associated with changes in postoperative PWV. Minimizing the treatment length and using postoperative beta blockers may attenuate the effects of prostheses on postoperative PWV.

Indexed as

Aortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationAorta, ThoracicBlood Vessel ProsthesisHumansPulse Wave AnalysisStentsTreatment OutcomeAortic arch aneurysmFrozen elephant trunkGraft replacementHybrid surgeryPulse wave velocityTreatment length

Identifiers

PMID34871404
PMCPMC8972244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.