Evidence map›Paper›PMID 34871212›Full record

ArticleMedicine2021

Clinical study on acupuncture treatment of gastrointestinal damp-heat acne.

Ping-Ping Duan, Chao-Qun Yan, Hui-Shang Feng, Yuan Chen, Ning Sun, Ya-Qi Yao, Kai-Bing Tian, Guang-An Wang

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ping-Ping DuanSchool of Acupuncture-Moxibustion and Tuina, Henan University of Chinese Medicine, 63 Dongming Road, Jinshui District, Henan, China.
Chao-Qun YanDepartment of Acupuncture and Moxibustion, Dongzhimen Hospital Beijing University of Chinese Medicine, Hai Yun Cang on the 5th Zip, Dongcheng District, Beijing, China.ORCID 0000-0001-7921-3057
Hui-Shang FengDepartment of Acupuncture and Moxibustion, Dongzhimen Hospital Beijing University of Chinese Medicine, Hai Yun Cang on the 5th Zip, Dongcheng District, Beijing, China.
Yuan ChenFourth Department of Obstetrics and Gynecology, Zhumadian Traditional Chinese Medicine Hospital, No.895 Jiefang Road, Yicheng District, Zhumadian, Henan Province, China.
Ning SunSchool of Acupuncture-Moxibustion and Tuina, Henan University of Chinese Medicine, 63 Dongming Road, Jinshui District, Henan, China.
Ya-Qi YaoSchool of Acupuncture-Moxibustion and Tuina, Henan University of Chinese Medicine, 63 Dongming Road, Jinshui District, Henan, China.
Kai-Bing TianDepartment of Neurosurgery, Capital Medical University, Beijing Tiantan Hospital, No. 199, Nan Si Huan Xi Road, Beijing 100010, China.
Guang-An WangSchool of Acupuncture-Moxibustion and Tuina, Henan University of Chinese Medicine, 63 Dongming Road, Jinshui District, Henan, China.
First Affiliated Hospital of Henan University · CNBeijing University of Chinese Medicine · CNBeijing Tian Tan Hospital · CNZhumadian Central Hospital · CN

Funding

National Natural Science Foundation of China 81802683Project for new teachers of Beijing University of Chinese Medicine 2020-JYB-XJSJJ-045
6 · The paper itself

Abstract

backgroundAcne is a common inflammatory disease of sebaceous glands, which brings extensive emotional and psychological distress to patients. Although acupuncture has certain advantages in the treatment of acne, the curative effect is not exact. The purpose of this trial is to evaluate the feasibility, preliminary efficacy, and safety of the "Spleen and Stomach Guiyuan Acupuncture Method" (SSGA) in the treatment of gastrointestinal damp-heat acne.

methodsThe proposed protocol is planned as a randomized, assessor-blind, conventional-treatment-controlled trial to evaluate the efficacy of SSGA on gastrointestinal damp-heat acne. Seventy six gastrointestinal damp-heat acne patients will be randomly divided into 2 groups and receive SSGA or conventional acupuncture treatment. The entire study period is 12 weeks, including an 8-week treatment period and a 4-week follow-up period. All patients will receive 16 sessions of acupuncture treatment over 8 weeks. The primary outcome is the investigation global assessment (IGA) at week 8, which is an overall assessment of the degree of the inflammatory and non-inflammatory lesion. The secondary outcomes include IGA, the total facial lesion count (Total Lesion Count), the acne-specific quality of life, etc at weeks 8 and 12. The Expectation and Credibility of treatment rating scale will be used to measure the patients' attitudes to acupuncture after the first treatment. Adverse events will also be recorded. DISCUSSION: This study is helpful to evaluate the feasibility, preliminary efficacy, and safety of SSGA in the treatment of gastrointestinal damp-heat acne. The results will be used in sample size calculations for subsequent large-scale studies.Trial registration: Chinese Clinical Trial Registry ChiCTR2100047363. Registered on June 13, 2021.

Indexed as

Acupuncture TherapyAcne VulgarisHot TemperatureHumansImmunoglobulin AQuality of LifeRandomized Controlled Trials as TopicTreatment OutcomeImmunoglobulin A

Identifiers

PMID34871212
PMCPMC8568399
OpenAlexW4200189409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.