Evidence map›Paper›PMID 34871062›Full record

ArticleMolecular and cellular biology2022

Cxcl10 Chemokine Induces Migration of ING4-Deficient Breast Cancer Cells via a Novel Cross Talk Mechanism between the Cxcr3 and Egfr Receptors.

Emily Tsutsumi, Jeremiah Stricklin, Emily A Peterson, Joyce A Schroeder, Suwon Kim

Open access · greenAbstract read
In one paragraph

Article in Molecular and cellular biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Targeting CXCL9/10/11-CXCR3 axis: an important component of tumor-promoting and antitumor immunity.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Emily TsutsumiClinical Translational Sciences Program, College of Medicine-Phoenix, University of Arizona, Phoenix, Arizona, USA.
Jeremiah StricklinCancer and Cell Biology Division, Translational Genomics Research Institutegrid.250942.8, Phoenix, Arizona, USA.
Emily A PetersonCancer and Cell Biology Division, Translational Genomics Research Institutegrid.250942.8, Phoenix, Arizona, USA.
Joyce A SchroederMolecular and Cellular Biology, University of Arizona, Tucson, Arizona, USA.
Suwon KimClinical Translational Sciences Program, College of Medicine-Phoenix, University of Arizona, Phoenix, Arizona, USA.ORCID 0000-0003-0633-3183
Translational Genomics Research Institute · USUniversity of Arizona · US

Funding

Uranium as an Environmental Risk Factor for Cancer Among the NavajoU54CA143924 · NCI · UNIVERSITY OF ARIZONA · PI Melissa Marie Herbst-Kralovetz, JUANITA L. MERCHANT · 2009 to 2026
$26.7M
Ignite-Engage-Sustain: A Comprehensive Approach to Motivate, Involve, Educate, and Mentor Native American Students and Their Communities in Cancer Prevention, Treatment and ResearchR25CA221777 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MAURICE GODFREY, Regina Emily Idoate · 2017 to 2026
$4.0M
NCI NIH HHS R25 CA221777NCI NIH HHS U54 CA143924
6 · The paper itself

Abstract

The chemokine Cxcl10 has been associated with poor prognosis in breast cancer, but the mechanism is not well understood. Our previous study has shown that

Indexed as

BreastBreast NeoplasmsCell Cycle ProteinsCell Line, TumorChemokine CXCL10ErbB ReceptorsGenes, Tumor SuppressorHomeodomain ProteinsHumansReceptors, CXCR3Tumor Suppressor ProteinsCell Cycle ProteinsChemokine CXCL10CXCL10 protein, humanCXCR3 protein, humanEGFR protein, humanErbB ReceptorsHomeodomain ProteinsING4 protein, humanReceptors, CXCR3Tumor Suppressor Proteinsbreast cancercell migrationCXCL10 chemokineCXCR3 G protein-coupled receptorEgfrING4 tumor suppressor

Identifiers

PMID34871062
PMCPMC8852701
OpenAlexW4200112432

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.