Evidence map›Paper›PMID 34871039›Full record

ArticleInfection and immunity2022

Identifying Targets of Protective Antibodies against Severe Malaria in Papua, Indonesia, Using Locally Expressed Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1.

Janavi S Rambhatla, Gerry Q Tonkin-Hill, Eizo Takashima, Takafumi Tsuboi, Rintis Noviyanti, Leily Trianty, Boni F Sebayang, Daniel A Lampah, Jutta Marfurt, Ric N Price and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 5 countries.

Janavi S RambhatlaDepartment of Medicine (Royal Melbourne Hospital), The University of Melbournegrid.1008.9, Melbourne, Victoria, Australia.
Gerry Q Tonkin-HillBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Eizo TakashimaDivision of Malaria Research, Proteo-Science Center, Ehime Universitygrid.255464.4, Matsuyama, Japan.
Takafumi TsuboiDivision of Malaria Research, Proteo-Science Center, Ehime Universitygrid.255464.4, Matsuyama, Japan.
Rintis NoviyantiThe Eijkman Institute for Molecular Biologygrid.418754.b, Jakarta, Indonesia.
Leily TriantyThe Eijkman Institute for Molecular Biologygrid.418754.b, Jakarta, Indonesia.
Boni F SebayangThe Eijkman Institute for Molecular Biologygrid.418754.b, Jakarta, Indonesia.
Daniel A LampahTimika Malaria Research Program, Papuan Health and Community Development Foundation, Timika, Indonesia.
Jutta MarfurtGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Australia.
Ric N PriceGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Australia.
Nicholas M AnsteyGlobal and Tropical Health Division, Menzies School of Health Researchgrid.271089.5, Charles Darwin University, Darwin, Australia.
Anthony T PapenfussBioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Timon DamelangDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbournegrid.1008.9, Melbourne, Australia.
Amy W ChungDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbournegrid.1008.9, Melbourne, Australia.
Michael F DuffySchool of Biosciences, Bio21 Institute, University of Melbournegrid.1008.9, Melbourne, Australia.
Stephen J RogersonDepartment of Medicine (Royal Melbourne Hospital), The University of Melbournegrid.1008.9, Melbourne, Victoria, Australia.ORCID 0000-0003-4287-1982
The University of Melbourne · AUEijkman Institute for Molecular Biology · IDCharles Darwin University · AUEhime University · JPThe Royal Melbourne Hospital · AUMahidol University · TH

Funding

Department of Health | National Health and Medical Research Council (NHMRC) GNT1092789Department of Health | National Health and Medical Research Council (NHMRC) GNT1116955Department of Health | National Health and Medical Research Council (NHMRC) GNT1135820Department of Health | National Health and Medical Research Council (NHMRC) GNT1140509JSPS Kakenhi JP21H02724Wellcome Trust 200909Wellcome Trust 200909/Z/16/Z
6 · The paper itself

Abstract

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), a diverse family of multidomain proteins expressed on the surface of malaria-infected erythrocytes, is an important target of protective immunity against malaria. Our group recently studied transcription of the

Indexed as

MalariaMalaria, FalciparumAdultAntibodies, ProtozoanChildErythrocytesHumansIndonesiaMembrane ProteinsPlasmodium falciparumProtozoan ProteinsAntibodies, ProtozoanMembrane ProteinsProtozoan Proteinshumoral immunityIndonesiaPfEMP1Plasmodium falciparumsevere malaria

Identifiers

PMID34871039
PMCPMC8853675
OpenAlexW4200302535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.