Evidence map›Paper›PMID 34870825›Full record

ArticleJournal of ultrasound2022

Neuromuscular sonography detects changes in muscle echotexture and nerve diameter in ICU patients within 24 h.

Catherine Bulinski, Maxime Viard, Alexander Vlazak, Kathrin Habig, Martin Juenemann, Christoph Best, Ingo Schirotzek, Manfred Kaps, Heidrun H Krämer

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In one paragraph

Article in Journal of ultrasound, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catherine BulinskiDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Maxime ViardDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Alexander VlazakDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Kathrin HabigDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Martin JuenemannDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Christoph BestDepartment of Neurology, Phillipps University, Baldingerstrasse 1, Marburg, Germany.
Ingo SchirotzekDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Manfred KapsDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.
Heidrun H KrämerDepartment of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany. Heidrun.Kraemer@neuro.med.uni-giessen.de.ORCID http://orcid.org/0000-0003-0615-1304

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDuring an ICU stay, changes in muscles and nerves occur that is accessible via neuromuscular sonography.

methods17 patients recruited from the neurological and neurosurgical ICU (six women; 66 ± 3 years) and 7 healthy controls (three women, 75 ± 3 years) were included. Muscle sonography (rectus abdominis, biceps, rectus femoris and tibialis anterior muscles) using gray-scale values (GSVs), and nerve ultrasound (peroneal, tibial and sural nerves) analyzing the cross-sectional area (CSA) were performed on days 1 (t1), 3 (t2), 5 (t3), 8 (t4), and 16 (t5) after admission.

resultsTime course analysis revealed that GSVs were significantly higher within the patient group for all of the investigated muscles (rectus abdominis: F = 7.536; p = 0.011; biceps: F = 14.761; p = 0.001; rectus femoris: F = 9.455; p = 0.005; tibialis anterior: F = 7.282; p = 0.012). The higher GSVs were already visible at t1 or, at the latest, at t2 (tibialis anterior muscles). CSA was enlarged in all of the investigated nerves in the patient group (peroneal nerve: F = 7.129; p = 0.014; tibial nerve: F = 28.976, p < 0.001; sural nerve: F = 13.051; p = 0.001). The changes were visible very early (tibial nerve: t1; peroneal nerve: t2). The CSA of the motor nerves showed an association with the ventilation time and days within the ICU (t1 through t4; p < 0.05). DISCUSSION: We detected very early changes in the muscles and nerves of ICU-patients. Nerve CSA might be a useful parameter to identify patients who are at risk for difficult weaning. Therefore our observations might be severity signs of neuromuscular suffering for the most severe patients.

Indexed as

Muscle, SkeletalTibial NerveFemaleHumansIntensive Care UnitsSural NerveUltrasonographyCross-sectional areaGray-scale analysisICU-AWMuscle ultrasoundNerve ultrasound

Identifiers

PMID34870825
PMCPMC9402876

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