Evidence map›Paper›PMID 34870765›Full record

ArticleJournal of mathematical biology2021

Haldane's formula in Cannings models: the case of moderately strong selection.

Florin Boenkost, Adrián González Casanova, Cornelia Pokalyuk, Anton Wakolbinger

Abstract read
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In one paragraph

Article in Journal of mathematical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Florin BoenkostGoethe-Universität Frankfurt, FB 12, 60054, Frankfurt, Germany. boenkost@math.uni-frankfurt.de.ORCID 0000-0001-6268-5525
Adrián González CasanovaInstituto de Matemáticas, Universidad Nacional Autónoma de México, Área de la Investigación Científica, Circuito Exterior, Ciudad Universitaria, 04510, Coyoacán, CDMX, Mexico.
Cornelia PokalyukGoethe-Universität Frankfurt, FB 12, 60054, Frankfurt, Germany.
Anton WakolbingerGoethe-Universität Frankfurt, FB 12, 60054, Frankfurt, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For a class of Cannings models we prove Haldane's formula, [Formula: see text], for the fixation probability of a single beneficial mutant in the limit of large population size N and in the regime of moderately strong selection, i.e. for [Formula: see text] and [Formula: see text]. Here, [Formula: see text] is the selective advantage of an individual carrying the beneficial type, and [Formula: see text] is the (asymptotic) offspring variance. Our assumptions on the reproduction mechanism allow for a coupling of the beneficial allele's frequency process with slightly supercritical Galton-Watson processes in the early phase of fixation.

Indexed as

ReproductionPopulation DensityProbabilityBranching process approximationCannings modelDirectional selectionProbability of fixation

Identifiers

PMID34870765
PMCPMC8648686

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.