Evidence map›Paper›PMID 34870614›Full record

ArticleCMAJ open

Building the What Comes Next Cohort for

Fahima Dossa, Kelly Metcalfe, Rinku Sutradhar, Tari Little, Andrea Eisen, Kathy Chun, Wendy S Meschino, Lea Velsher, Jordan Lerner Ellis, Nancy N Baxter

Open access · diamondAbstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Trends in the Utilization ofCurrent oncology (Toronto, Ont.) · 2025
    Article
  4. Longitudinal adherence to surveillance for late effects of cancer treatment: a population-based study of adult survivors of childhood cancer.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

Fahima DossaDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Kelly MetcalfeDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Rinku SutradharDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Tari LittleDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Andrea EisenDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Kathy ChunDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Wendy S MeschinoDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Lea VelsherDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Jordan Lerner EllisDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia.
Nancy N BaxterDivision of General Surgery, Department of Surgery (Dossa), Institute of Health Policy, Management and Evaluation (Dossa, Sutradhar, Baxter), Lawrence S. Bloomberg Faculty of Nursing ( Metcalfe) Division of Biostatistics, Dalla Lana School of Public Health (Sutradhar), Department of Pediatrics (Meschino) and Department of Laboratory Medicine and Pathobiology (Lerner Ellis), University of Toronto; ICES Central (Sutradhar); Department of Surgery (Little), St. Michael's Hospital; Odette Cancer Centre (Eisen), Sunnybrook Health Sciences Centre; Department of Paediatric Laboratory Medicine (Chun), The Hospital for Sick Children; Genetics Program (Meschino, Velsher), North York General Hospital; Lunenfeld-Tanenbaum Research Institute (Lerner Ellis) and Pathology and Laboratory Medicine (Lerner Ellis), Mount Sinai Hospital, Sinai Health System, Toronto, Ont.; Melbourne School of Population and Global Health (Baxter), University of Melbourne, Melbourne, Victoria, Australia Nancy.Baxter@unimelb.edu.au.
Health Sciences Centre · CASunnybrook Health Science Centre · CAUniversity of Melbourne · AUHospital for Sick Children · CAYork General Hospital · US

Funding

CIHR
6 · The paper itself

Abstract

backgroundOur understanding of how testing for and mutations of the

methodsThis descriptive study included adult women (≥ 18 yr) who met at least 1 of 13 provincial criteria for

resultsWe identified 15 986 women (mean age 52.5 [standard deviation 13.9] yr) who underwent

interpretationSeveral provincial eligibility criteria for

Indexed as

Genetic TestingAdultAgedBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsFemaleGenes, BRCA1Genes, BRCA2Genetic Predisposition to DiseaseHumansIncidenceMiddle AgedMutationOntarioOvarian NeoplasmsBRCA1 ProteinBRCA2 Protein

Identifiers

PMID34870614
PMCPMC8741196
OpenAlexW3200513004

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.