ArticleJMIR formative research2021
Conversational Agent for Healthy Lifestyle Behavior Change: Web-Based Feasibility Study.
Article in JMIR formative research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07612800 (Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention (THINK-SHARP)
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review exploring human, AI, and hybrid health coaching in digital health interventions: trends, engagement, and lifestyle outcomes.Frontiers in digital health · 2025Pooled it
- Application of Chatbots to Help Patients Self-Manage Diabetes: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Web-Based Nutrition and Physical Activity Education Intervention to Ameliorate Cardiometabolic Risks: A Single-Arm and Non-Randomized Feasibility Study.Journal of primary care & community healthTrial
- Artificial Intelligence as a Personal Coach: A Narrative Review of Benefits and Risks in Educational and Health Contexts.Behavioral sciences (Basel, Switzerland) · 2026Review
- Assessing the User Experience of an LLM-Based Conversational Assistant in Diabetes Mellitus Care.Journal of healthcare informatics research · 2026Article
- The Development and Use of AI Chatbots for Health Behavior Change: Scoping Review.Journal of medical Internet research · 2026Article
- The effectiveness and acceptability of digital health interventions as tools to promote physical activity in primary care: an update scoping review.Primary health care research & development · 2025Article
- The ENGAGE study: evaluation of a conversational virtual agent that provides tailored pre-test genetic education to cancer patients.Journal of cancer survivorship : research and practice · 2025Article
- Prevalence and determinants of HealthHub app utilization among community-dwelling adults in Singapore.PloS one · 2025Article
- The potential and limitations of large language models in identification of the states of motivations for facilitating health behavior change.Journal of the American Medical Informatics Association : JAMIA · 2024Article
- Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.Journal of medical Internet research · 2024Review
- Assessing the Accuracy of Generative Conversational Artificial Intelligence in Debunking Sleep Health Myths: Mixed Methods Comparative Study With Expert Analysis.JMIR formative research · 2024Article
- Infusing behavior science into large language models for activity coaching.PLOS digital health · 2024Article
- Conversational Agents in Health Care: Expert Interviews to Inform the Definition, Classification, and Conceptual Framework.Journal of medical Internet research · 2023Article
- Factors Influencing the Acceptability, Acceptance, and Adoption of Conversational Agents in Health Care: Integrative Review.Journal of medical Internet research · 2023Review
- Systematic review and meta-analysis of the effectiveness of chatbots on lifestyle behaviours.NPJ digital medicine · 2023Review
- Conversational Agents and Avatars for Cardiometabolic Risk Factors and Lifestyle-Related Behaviors: Scoping Review.JMIR mHealth and uHealth · 2023Article
- Examining Patient Engagement in Chatbot Development Approaches for Healthy Lifestyle and Mental Wellness Interventions: Scoping Review.Journal of participatory medicine · 2023Article
- Adaptation of the Gabby conversational agent system to improve the sexual and reproductive health of young women in Lesotho.Frontiers in digital health · 2023Article
- Exploring views and experiences of the general public's adoption of digital technologies for healthy lifestyle in Singapore: a qualitative study.Frontiers in public health · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe rising incidence of chronic diseases is a growing concern, especially in Singapore, which is one of the high-income countries with the highest prevalence of diabetes. Interventions that promote healthy lifestyle behavior changes have been proven to be effective in reducing the progression of prediabetes to diabetes, but their in-person delivery may not be feasible on a large scale. Novel technologies such as conversational agents are a potential alternative for delivering behavioral interventions that promote healthy lifestyle behavior changes to the public.
objectiveThe aim of this study is to assess the feasibility and acceptability of using a conversational agent promoting healthy lifestyle behavior changes in the general population in Singapore.
methodsWe performed a web-based, single-arm feasibility study. The participants were recruited through Facebook over 4 weeks. The Facebook Messenger conversational agent was used to deliver the intervention. The conversations focused on diet, exercise, sleep, and stress and aimed to promote healthy lifestyle behavior changes and improve the participants' knowledge of diabetes. Messages were sent to the participants four times a week (once for each of the 4 topics of focus) for 4 weeks. We assessed the feasibility of recruitment, defined as at least 75% (150/200) of our target sample of 200 participants in 4 weeks, as well as retention, defined as 33% (66/200) of the recruited sample completing the study. We also assessed the participants' satisfaction with, and usability of, the conversational agent. In addition, we performed baseline and follow-up assessments of quality of life, diabetes knowledge and risk perception, diet, exercise, sleep, and stress.
resultsWe recruited 37.5% (75/200) of the target sample size in 1 month. Of the 75 eligible participants, 60 (80%) provided digital informed consent and completed baseline assessments. Of these 60 participants, 56 (93%) followed the study through till completion. Retention was high at 93% (56/60), along with engagement, denoted by 50% (30/60) of the participants communicating with the conversational agent at each interaction. Acceptability, usability, and satisfaction were generally high. Preliminary efficacy of the intervention showed no definitive improvements in health-related behavior.
conclusionsThe delivery of a conversational agent for healthy lifestyle behavior change through Facebook Messenger was feasible and acceptable. We were unable to recruit our planned sample solely using the free options in Facebook. However, participant retention and conversational agent engagement rates were high. Our findings provide important insights to inform the design of a future randomized controlled trial.
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