Evidence map›Paper›PMID 34870588›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022

Obstructive sleep apnea syndrome as a rare presentation in a young girl with a central nervous system tumor.

Fern Buller, Muhammad A Kamal, Samantha K Brown, Emma Carruthers, Mary-Louise Montague, Daniel Ochieng, Lesley A Simpson, Thomas C Williams, Chandrasekaran Kaliaperumal, Don S Urquhart

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Fern BullerDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Muhammad A KamalDepartment of Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Samantha K BrownDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Emma CarruthersDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Mary-Louise MontagueDepartment of ENT Surgery, Royal Hospital for Children and Young People, Edinburgh, United Kingdom.
Daniel OchiengDepartment of Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Lesley A SimpsonDepartment of Paediatric Oncology, Royal Hospital for Children and Young People, Edinburgh, United Kingdom.
Thomas C WilliamsDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Chandrasekaran KaliaperumalDepartment of Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
Don S UrquhartDepartment of Paediatric Respiratory and Sleep Medicine, Royal Hospital for Children and Young People, Edinburgh, UK.
Royal Hospital for Children · GBEdinburgh Royal Infirmary · GBUniversity of Edinburgh · GB

Funding

Wellcome Trust 204802/Z/16/Z
6 · The paper itself

Abstract

Sleep-related breathing disorders are a common problem in infancy and childhood. The most common type of sleep-related breathing disorder in this age group is obstructive sleep apnea syndrome (OSAS), generally caused by factors affecting airway patency, such as tonsillar hypertrophy or obesity. However, in adults OSAS can also be caused by processes affecting the brainstem, such as central nervous system tumors. This report describes a 2-year-old girl who presented with symptoms of snoring, restless sleep, repeated night-time waking, and apneic events while asleep. She had no comorbidities, and examination revealed normal-sized tonsils. A sleep study demonstrated severe OSAS with an obstructive apnea/hypopnea index of 34. Her OSAS completely resolved on excision of the tumor. The case highlights the importance of neurological examination as part of evaluation of OSAS, especially in cases where tonsils are not enlarged and there are no other risk factors for OSAS. CITATION: Buller F, Kamal MA, Brown SK, et al. Obstructive sleep apnea syndrome as a rare presentation in a young girl with a central nervous system tumor.

Indexed as

AdenoidsCentral Nervous System NeoplasmsSleep Apnea, ObstructiveAdultChildChild, PreschoolFemaleHumansPolysomnographySnoringbrain tumorobstructive sleep apnea syndromesleep-disordered breathing

Identifiers

PMID34870588
PMCPMC8974373
OpenAlexW4200314370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.