Evidence map›Paper›PMID 34870584›Full record

Trial reportJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022

Cannabis use as a moderator of cognitive behavioral therapy for insomnia.

Mary Beth Miller, Ryan W Carpenter, Lindsey K Freeman, Ashley F Curtis, Ali M Yurasek, Christina S McCrae

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03627832 (Insomnia Treatment and Problems), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03627832 nacompletednot on this map

Insomnia Treatment and Problems (the iTAP Study)

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2018 to 2019Enrolled56ConditionsInsomnia, Alcohol, Harmful UseArmsCognitive Behavioral Therapy for Insomnia (CBT-I), Sleep Hygiene
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Daily-level associations between sleep hygiene, cannabis use, and sleep health outcomes.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Mary Beth MillerDepartment of Psychiatry, University of Missouri School of Medicine, Columbia, Missouri.
Ryan W CarpenterDepartment of Psychological Sciences, University of Missouri-St. Louis, St. Louis, Missouri.
Lindsey K FreemanDepartment of Psychiatry, University of Missouri School of Medicine, Columbia, Missouri.
Ashley F CurtisDepartment of Psychiatry, University of Missouri School of Medicine, Columbia, Missouri.
Ali M YurasekHealth Education and Behavior Department, College of Health and Human Performance, University of Florida, Gainesville, Florida.
Christina S McCraeDepartment of Psychiatry, University of Missouri School of Medicine, Columbia, Missouri.
University of Missouri · USIn-Q-Tel · USUniversity of Florida Health · USUniversity of Missouri–St. Louis · US

Funding

Psychology of Alcohol Use and Dependence TrainingT32AA013526 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI DENIS M MCCARTHY, KENNETH JAMES SHER · 2002 to 2026
$9.0M
Impact of CBT for Insomnia on Pain Symptoms and Central Sensitization in Fibromyalgia.R01NR017168 · NINR · UNIVERSITY OF MISSOURI-COLUMBIA · PI MCCRAE, CHRISTINA S · 2018 to 2022
$3.4M
The Impact of Insomnia Treatment on Heavy Alcohol Use among Returning VeteransK23AA026895 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI MILLER, MARY ELIZABETH · 2019 to 2023
$896k
NIAAA NIH HHS K23 AA026895NIAAA NIH HHS T32 AA013526NINR NIH HHS R01 NR017168
6 · The paper itself

Abstract

STUDY

objectivesCannabis use is common among young adults and has been proposed as a potential treatment for insomnia. However, controlled studies examining the impact of cannabis use on insomnia symptoms are rare. This secondary analysis of published trial data tested cannabis use during cognitive behavioral treatment for insomnia (CBT-I) as a moderator of treatment efficacy.

methodsYoung adults (ages 18-30 years) who reported past-month binge drinking (4/5+ drinks for women/men) and met diagnostic criteria for insomnia disorder were randomized to CBT-I (n = 28) or sleep hygiene (n = 28) groups. Interaction effects were tested using multilevel models. Outcomes included insomnia severity, actigraphy-assessed sleep efficiency, diary-assessed sleep quality, drinking quantity, and alcohol-related consequences.

resultsTwenty-six participants (46%; 12 in the sleep hygiene group and 14 in the CBT-I group) reported using cannabis during the treatment phase of the study, on an average of 23% of treatment days (range, 3%-100%). Relative to those who did not use cannabis, participants who used cannabis during treatment reported heavier drinking and more frequent cigarette use. Approximately 1 in 4 cannabis users (27%) reported using cannabis to help with sleep; however, cannabis users and nonusers did not differ in the use of alcohol as a sleep aid. Controlling for sex, race, drinking quantity, cigarette use, symptoms of depression, and symptoms of anxiety, use of cannabis during treatment did not moderate CBT-I effects on insomnia severity (

conclusionsCBT-I is effective in reducing insomnia symptoms among young adult drinkers with insomnia, regardless of cannabis use. CLINICAL

trial registrationRegistry: ClinicalTrials.gov; Name: The Insomnia Treatment and Problems (iTAP) Study; URL: https://clinicaltrials.gov/ct2/show/NCT03627832; Identifier: NCT03627832. CITATION: Miller MB, Carpenter RW, Freeman LK, Curtis AF, Yurasek AM, McCrae CS. Cannabis use as a moderator of cognitive behavioral therapy for insomnia.

Indexed as

CannabisCognitive Behavioral TherapySleep Initiation and Maintenance DisordersActigraphyAdolescentAdultFemaleHumansMaleSleepTreatment OutcomeYoung Adultalcoholcannabisinsomniasleeptreatment

Identifiers

PMID34870584
PMCPMC8974363
OpenAlexW4200122963

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.