Evidence map›Paper›PMID 34870149›Full record

ArticleCurrent research in pharmacology and drug discovery2021

Potential inhibitors of SARS-CoV-2 (COVID 19) proteases PL

Devvret Verma, Debasis Mitra, Manish Paul, Priya Chaudhary, Anshul Kamboj, Hrudayanath Thatoi, Pracheta Janmeda, Divya Jain, Periyasamy Panneerselvam, Rakesh Shrivastav and 2 more

Abstract read
In one paragraph

Article in Current research in pharmacology and drug discovery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Article
  8. Exploring the Therapeutic Potential ofMolecules (Basel, Switzerland) · 2024
    Article
  9. Review
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  11. Article
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  18. 3 Biotech · 2022
    Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Devvret VermaDepartment of Biotechnology, Graphic Era (Deemed to be University), Dehradun, 248 002, Uttarakhand, India.
Debasis MitraDepartment of Microbiology, Raiganj University, Raiganj, 733 134, Uttar Dinajpur, West Bengal, India.
Manish PaulDepartment of Biotechnology, Maharaja Sriram Chandra Bhanja Deo University, Baripada, 757003, Odisha, India.
Priya ChaudharyDepartment of Bioscience and Biotechnology, Banasthali University, Vanasthali, 304022, Rajasthan, India.
Anshul KambojDepartment of Biotechnology, Graphic Era (Deemed to be University), Dehradun, 248 002, Uttarakhand, India.
Hrudayanath ThatoiDepartment of Biotechnology, Maharaja Sriram Chandra Bhanja Deo University, Baripada, 757003, Odisha, India.
Pracheta JanmedaDepartment of Bioscience and Biotechnology, Banasthali University, Vanasthali, 304022, Rajasthan, India.
Divya JainDepartment of Bioscience and Biotechnology, Banasthali University, Vanasthali, 304022, Rajasthan, India.
Periyasamy PanneerselvamMicrobiology, Crop Production Division, ICAR- National Rice Research Institute, Cuttack, 753 006, Odisha, India.
Rakesh ShrivastavDepartment of Applied Sciences, NGF College of Engineering and Technology, Palwal, Haryana, India.
Kumud PantDepartment of Biotechnology, Graphic Era (Deemed to be University), Dehradun, 248 002, Uttarakhand, India.
Pradeep K Das MohapatraDepartment of Microbiology, Raiganj University, Raiganj, 733 134, Uttar Dinajpur, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - coronavirus disease 2019 (COVID-19) has raised a severe global public health issue and creates a pandemic situation. The present work aims to study the molecular -docking and dynamic of three pertinent medicinal plants

Indexed as

Canthin-6-one 9-O-Beta-glucopyranosideMolecular dynamicsNatural inhibitorPLpro-Mpro/3CLproSARS-CoV-2 (COVID-19)

Identifiers

PMID34870149
PMCPMC8178537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.