Evidence map›Paper›PMID 34870139›Full record

ArticleMetabolism open2021

Protective effects of cerium oxide nanoparticles in non-alcoholic fatty liver disease (NAFLD) and carbon tetrachloride-induced liver damage in rats: Study on intestine and liver.

Ebrahim Abbasi, Seyed Alireza Vafaei, Nima Naseri, Ali Darini, Masoumeh Taheri Azandaryani, Farhad Kian Ara, Fatemeh Mirzaei

Open access · goldAbstract read
In one paragraph

Article in Metabolism open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Radioprotective Potency of Nanoceria.Current radiopharmaceuticals · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ebrahim AbbasiDepartment of Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Seyed Alireza VafaeiDepartment of Biology, Islamic Azad University, Sanandaj Branch, Sanandaj, Iran.
Nima NaseriDepartment of Biochemistry, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Ali DariniDepartment of Nanotechnology, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran.
Masoumeh Taheri AzandaryaniDepartment of Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Farhad Kian AraMedical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Fatemeh MirzaeiDepartment of Anatomy, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Hamedan University of Medical Sciences · IRIslamic Azad University Pharmaceutical Sciences Branch · IRIslamic Azad University Sanandaj Branch · IRKermanshah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsNanoparticles could represent a therapeutic approach for the treatment of various diseases. It has been reported that cerium oxide nanoparticles (CeO

methodsIn this experimental study, male rats were randomly divided into different experimental groups including: Experiment 1; group1: healthy rats received normal saline, 2: CCl

resultsTotal antioxidant capacity (TAC) and glutathione (GSH) levels significantly decreased, while malondialdehyde (MDA) and total oxidant status (TOS) were significantly increased in the liver, and intestine of the NAFLD and CCl

conclusionsOur finding revealed that CeO

Indexed as

Carbon tetrachlorideCerium oxide nanoparticlesInflammationLiver injuryRats

Identifiers

PMID34870139
PMCPMC8626579
OpenAlexW3217685383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.