ArticlePsychiatric research and clinical practice2021
Opioid Use Disorder in Women and the Implications for Treatment.
Article in Psychiatric research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed.
- Clinical and psychosocial outcomes by sex among individuals prescribed buprenorphine-naloxone (BUP-NX) or extended-release naltrexone (XR-NTX) for opioid use disorder.The American journal on addictions · 2023Trial
- Reproductive health considerations for HIV prevention integrated care models for women who inject drugs: Qualitative perspective of participants and providers in HIV Prevention Trials Network 094.Drug and alcohol dependence · 2026Article
- Barriers and Facilitators to Sexual and Reproductive Healthcare for Women in Opioid Use Disorder Recovery: Perspectives from Recovery Healthcare Professionals.Healthcare (Basel, Switzerland) · 2026Article
- Paternal inheritance of a vulnerable opioid-taking phenotype in female rats.bioRxiv : the preprint server for biology · 2026Article
- Transitions from first drug use to illicit opioid and injection drug use in a multisite rural U.S. cohort of people who use drugs.Harm reduction journal · 2026Article
- Not just neurons: glial mechanisms driving sex-specific vulnerability to withdrawal and relapse in substance use disorder.Frontiers in neuroendocrinology · 2026Review
- Identifying Sex Differences in Adverse Events Reported on Opioid Drugs in the FDA's Adverse Event Reporting System (FAERS).Pharmaceuticals (Basel, Switzerland) · 2026Article
- The evolving epidemiology of opioid use disorder: polysubstance use, drug supply transformation, and policy implications.Frontiers in public health · 2026Review
- Gender-specific addiction research needed now more than ever: Reflections from 25 years of the NIDA Clinical Trials Network Gender Special Interest Group.Journal of substance use and addiction treatment · 2025Article
- When the Heart Hurts the Kidneys: From Flow to Translational Future.Seminars in nephrology · 2025Review
- Overdose Data to Action: A qualitative analysis of funded activities tailored for women.Journal of substance use and addiction treatment · 2025Article
- Social Safety Net Programs: The Relationship With Drug Treatment Among Women.American journal of preventive medicine · 2025Article
- Gender and Overdose Risk Factors Among Clients Entering Residential Treatment for Opioid Use.Drug and alcohol review · 2025Article
- The role of micro-, meso-, and macro-level stigma on the uptake of medications for opioid use disorder (MOUD) among women in the criminal legal system.BMC women's health · 2025Article
- The benefits and potential biases of lived experience in substance use treatment services.Journal of social work practice in the addictions · 2025Article
- Estradiol protects against pain-facilitated fentanyl use via suppression of opioid-evoked dopamine activity in males.Neuron · 2025Article
- Severity of post-traumatic stress and non-medical, concomitant opioid and benzodiazepine use in a sample of women at high risk of overdose.International journal of mental health and addiction · 2025Article
- Article
- Examining the association between fentanyl use and perceived adequacy of methadone dose: A retrospective cohort study.Drug and alcohol dependence · 2025Article
- Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveThe opioid epidemic continues to evolve and impact all groups of people. Moreover, there are concerning trends among women. The aim of this article is to provide a review of opioid use disorder in women and the implications for treatment.
methodsA nonsystematic review of the literature as conducted to examine: (1) the epidemiology of opioid-related hospitalizations and deaths of women; (2) co-occurring pain, anxiety disorders, and trauma among women with opioid use disorder; (3) evidence for opioid agonist treatment of pregnant women with opioid use disorder; and (4) implications for treatment of women with opioid use disorder and next steps for research and practice.
resultsThe current opioid epidemic has produced important differences by sex and gender with increased rates of use and overdose deaths in women. Significant mental health concerns for women include co-occurring psychiatric disorders and suicide. Expanding medication treatment for perinatal opioid use disorder is crucial. While effective treatments exist for opioid use disorder, they are often not accessible, and a minority of patients are treated.
conclusionsThe end to the opioid epidemic will require innovative multi-systemic solutions. There are significant practice gaps in preventing rising death rates among women by opioid overdose, treating co-occurring psychiatric disorders and pain, and treating perinatal women with opioid use disorder and their infants. Research on sex and gender differences, and the intersection with race/ethnicity and US region, is critically needed and should include treatment implementation studies to achieve wider access for women to effective prevention, early intervention, and treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.