Evidence map›Paper›PMID 34870025›Full record

ArticleACS omega2021

Lipid-Based Nutrient Supplementation Increases High-Density Lipoprotein (HDL) Cholesterol Efflux Capacity and Is Associated with Changes in the HDL Glycoproteome in Children.

Brian V Hong, Chenghao Zhu, Maurice Wong, Romina Sacchi, Christopher H Rhodes, Jea Woo Kang, Charles D Arnold, Seth Adu-Afarwuah, Anna Lartey, Brietta M Oaks and 3 more

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. HDL Function across the Lifespan: From Childhood, to Pregnancy, to Old Age.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Brian V HongDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.ORCID https://orcid.org/0000-0001-7080-2744
Chenghao ZhuDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.
Maurice WongDepartment of Chemistry, University of California, Davis, Davis 95616, California, United States.ORCID https://orcid.org/0000-0003-3851-2928
Romina SacchiDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.
Christopher H RhodesDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.
Jea Woo KangDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.
Charles D ArnoldDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.
Seth Adu-AfarwuahDepartment of Nutrition and Food Science, University of Ghana, Legon LG 134, Ghana.
Anna LarteyDepartment of Nutrition and Food Science, University of Ghana, Legon LG 134, Ghana.
Brietta M OaksDepartment of Nutrition and Food Sciences, University of Rhode Island, Kingston 02881-2003, Rhode Island, United States.
Carlito B LebrillaDepartment of Chemistry, University of California, Davis, Davis 95616, California, United States.ORCID https://orcid.org/0000-0001-7190-5323
Kathryn G DeweyDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.
Angela M ZivkovicDepartment of Nutrition, University of California, Davis, Davis 95616, California, United States.ORCID https://orcid.org/0000-0002-2828-7862
University of California, Davis · USUniversity of Ghana · GHUniversity of Rhode Island · US

Funding

Novel Separation Methods for exRNA Carriers: Extracellular Vesicles, Lipoprotein Particles, and Protein AggregatesUH3CA241694 · NCI · JOHNS HOPKINS UNIVERSITY · PI WITWER, KENNETH W · 2021 to 2022
$1.1M
Novel Separation Methods for exRNA Carriers: Extracellular Vesicles, Lipoprotein Particles, and Protein AggregatesUG3CA241694 · NCI · JOHNS HOPKINS UNIVERSITY · PI WITWER, KENNETH W · 2019 to 2020
$941k
NCI NIH HHS UG3 CA241694NCI NIH HHS UH3 CA241694
6 · The paper itself

Abstract

Prenatal plus postnatal small-quantity lipid-based nutrient supplements (SQ-LNS) improved child growth at 18 months in the International Lipid-Based Nutrient Supplements DYAD trial in Ghana. In this secondary outcome analysis, we determined whether SQ-LNS versus prenatal iron and folic acid (IFA) supplementation improves the cholesterol efflux capacity (CEC) of high-density lipoprotein (HDL) particles and alters their lipidomic, proteomic, or glycoproteomic composition in a subset of 80 children at 18 months of age. HDL CEC was higher among children in the SQ-LNS versus IFA group (20.9 ± 4.1 vs 19.4 ± 3.3%; one-tailed

Identifiers

PMID34870025
PMCPMC8638293
OpenAlexW3217306101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.