Evidence map›Paper›PMID 34869908›Full record

ArticleTrauma surgery & acute care open2021

Comparing trauma mortality of injured patients in India and the USA: a risk-adjusted analysis.

Stas Amato, Levi Bonnell, Monali Mohan, Nobhojit Roy, Ajai Malhotra

Abstract read
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Article in Trauma surgery & acute care open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

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9citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Stas AmatoDepartment of General Surgery, University of Vermont Medical Center, Burlington, Vermont, USA.ORCID 0000-0003-4403-0247
Levi BonnellDepartment of General Internal Medicine, University of Vermont Medical Center, Burlington, Vermont, USA.
Monali MohanDepartment of Health Systems Strengthening, Care India, Bihar, Patna, India.
Nobhojit RoyThe George Institute for Global Health, New Delhi, India.ORCID 0000-0003-2022-7416
Ajai MalhotraDepartment of General Surgery, University of Vermont Medical Center, Burlington, Vermont, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesComparisons of risk-adjusted trauma mortality between high-income countries and low and middle-income countries (LMICs) can be used to identify specific patient populations and injury patterns for targeted interventions. Due to a paucity of granular patient and injury data from LMICs, there is a lack of such comparisons. This study aims to identify independent predictors of trauma mortality and significant differences between India and the USA.

methodsA retrospective cohort study of two trauma databases was conducted. Demographic, injury, physiologic, anatomic and outcome data were analyzed from India's Towards Improved Trauma Care Outcomes project database and the US National Trauma Data Bank from 2013 to 2015. Multivariate logistic regression analyses were performed to determine significant independent predictors of mortality.

results687 407 adult trauma patients were included (India 11 796; USA 675 611). Patients from India were significantly younger with greater male preponderance, a higher proportion presented with physiologic abnormalities and suffered higher mortality rates (23.2% vs. 2.8%). When controlling for age, sex, physiologic abnormalities, and injury severity, sustaining an injury in India was the strongest predictor of mortality (OR 13.85, 95% CI 13.05 to 14.69). On subgroup analyses, the greatest mortality difference was seen in patients with lower Injury Severity Scores.

conclusionAfter adjusting for demographic, physiologic abnormalities, and injury severity, trauma-related mortality was found to be significantly higher in India. When compared with trauma patients in the USA, the odds of mortality are most notably different among patients with lower Injury Severity Scores. While troubling, this suggests that relatively simple, low-cost interventions focused on standard timely trauma care, early imaging, and protocolized treatment pathways could result in substantial improvements for injury mortality in India, and potentially other LMICs. LEVEL OF EVIDENCE: Level 3, retrospective cohort study.

Indexed as

epidemiologyhealthcare disparitiesIndiamultiple trauma

Identifiers

PMID34869908
PMCPMC8603298

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.