Evidence map›Paper›PMID 34869814›Full record

ArticleJAAD case reports2021

Bespoke circulating tumor DNA as a biomarker for treatment response in a refractory Merkel cell carcinoma patient.

John Yeakel, Aarthi Kannan, Nicole Hook Rattigan, Maki Yamamoto, Alexey Aleshin, Jeremy P Harris, Ling Gao

Open access · goldAbstract readCase Reports
In one paragraph

Article in JAAD case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. The Evolving Treatment Landscape of Merkel Cell Carcinoma.Current treatment options in oncology · 2023
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

John YeakelDepartment of Radiation Oncology, University of California, Irvine, California.
Aarthi KannanDepartment of Dermatology, University of California, Irvine, California.
Nicole Hook RattiganNatera, Inc, Austin, Texas.
Maki YamamotoDepartment of Surgery, University of California, Irvine, California.
Alexey AleshinNatera, Inc, Austin, Texas.
Jeremy P HarrisDepartment of Radiation Oncology, University of California, Irvine, California.
Ling GaoDepartment of Dermatology, University of California, Irvine, California.
University of California, Irvine · USNatera (United States) · USSouthern California Institute for Research and Education · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Melanie Funes · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

circulating tumor DNACT, computed tomographyCtDNA, cell-free circulating tumor DNAHRT, hypofractionated radiationhypofractionated radiationICIs, immune checkpoint inhibitorsMCC, Merkel cell carcinomaMerkel cell carcinomaMTM, mean tumor moleculesT-VECT-VEC, talimogene laherparepvec

Identifiers

PMID34869814
PMCPMC8626794
OpenAlexW3210351033

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.