Evidence map›Paper›PMID 34869695›Full record

ReviewFrontiers in cardiovascular medicine2021

The Pivotal Role of Invasive Functional Assessment in Patients With Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA).

Fabio Mangiacapra, Michele Mattia Viscusi, Luca Paolucci, Annunziata Nusca, Rosetta Melfi, Gian Paolo Ussia, Francesco Grigioni

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Coronary microvascular dysfunction is a hallmark of all subtypes of MINOCA.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Fabio MangiacapraUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Michele Mattia ViscusiUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Luca PaolucciUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Annunziata NuscaUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Rosetta MelfiUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Gian Paolo UssiaUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Francesco GrigioniUnit of Cardiovascular Science, Department of Medicine, Campus Bio-Medico University, Rome, Italy.
Università Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction with non-obstructive coronary arteries (MINOCA) encompasses several pathophysiological mechanisms not yet fully understood. Among the latter, vasomotion abnormalities and coronary microvascular dysfunction (CMD) play a major role for both epidemiological and prognostic reasons. Despite current guidelines do not recommend routine physiological assessment of both epicardial and microvascular coronary compartments within the context of an acute myocardial infarction, several recent evidence support the critical role of a comprehensive invasive functional assessment in order to identify the underlying pathophysiological mechanism and consequently to select an appropriate therapeutic strategy. Unfortunately, optimal medical therapy for these patients is not currently established due to the lack of dedicated trials evaluating clinical outcomes of commonly used medications for secondary prevention in MINOCA patients. For this reason, additional research is warranted to provide personalized treatments for patients affected by this puzzling clinical entity.

Indexed as

acute coronary syndromecoronary artery diseasecoronary physiologymicrovascular dysfunctionMINOCA

Identifiers

PMID34869695
PMCPMC8637881
OpenAlexW3211626631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.