Evidence map›Paper›PMID 34869510›Full record

ReviewFrontiers in nutrition2021

Progress on Gut Health Maintenance and Antibiotic Alternatives in Broiler Chicken Production.

Qidong Zhu, Peng Sun, Bingkun Zhang, LingLian Kong, Chuanpi Xiao, Zhigang Song

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
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  8. The sambiloto (Journal of advanced veterinary and animal research · 2026
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  14. Supplementation ofAnimals : an open access journal from MDPI · 2025
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  16. Animals : an open access journal from MDPI · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qidong ZhuDepartment of Animal Science, Shandong Agricultural University, Taian, China.
Peng SunDepartment of Nutrition Technology, Shandong Hekangyuan Cooperation, Jinan, China.
Bingkun ZhangDepartment of Animal Science, China Agricultural University, Beijing, China.
LingLian KongDepartment of Animal Science, Shandong Agricultural University, Taian, China.
Chuanpi XiaoDepartment of Animal Science, Shandong Agricultural University, Taian, China.
Zhigang SongDepartment of Animal Science, Shandong Agricultural University, Taian, China.
Shandong Agricultural University · CNChina Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The perturbation of gut health is a common yet unresolved problem in broiler chicken production. Antibiotics used as growth promoters have remarkably improved the broiler production industry with high feed conversion efficiency and reduced intestinal problems. However, the misuse of antibiotics has also led to the increase in the development of antibiotic resistance and antibiotic residues in the meat. Many countries have enacted laws prohibiting the use of antibiotics in livestock production because of the increasing concerns from the consumers and the public. Consequently, one of the most significant discussions in the poultry industry is currently antibiotic-free livestock production. However, the biggest challenge in animal husbandry globally is the complete removal of antibiotics. The necessity to venture into antibiotic-free production has led researchers to look for alternatives to antibiotics in broiler chicken production. Many strategies can be used to replace the use of antibiotics in broiler farming. In recent years, many studies have been conducted to identify functional feed additives with similar beneficial effects as antibiotic growth promoters. Attention has been focused on prebiotics, probiotics, organic acids, emulsifiers, enzymes, essential oils, tributyrin, and medium-chain fatty acids. In this review, we focused on recent discoveries on gut health maintenance through the use of these functional feed additives as alternatives to antibiotics in the past 10 years to provide novel insights into the design of antibiotic-free feeds.

Indexed as

antibioticantibiotic-free strategiesbroilersguthealth

Identifiers

PMID34869510
PMCPMC8636040
OpenAlexW3213603402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.