Evidence map›Paper›PMID 34869505›Full record

SynthesisFrontiers in medicine2021

Therapeutic Effect and Safety of Granulocyte Colony-Stimulating Factor Therapy for Acute-On-Chronic Liver Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Xiaoxue Hou, Yuwen Li, Hui Yuan, Jinyuan Cai, Rui Liu, Jun Li, Chuanlong Zhu

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. The Impact of Liver Failure on the Immune System.International journal of molecular sciences · 2024
    Review
  7. Pediatric Acute-on-Chronic Liver Failure.Indian journal of pediatrics · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoxue HouDepartment of Infectious Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yuwen LiDepartment of Pediatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hui YuanDepartment of Infectious Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jinyuan CaiDepartment of Infectious Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Rui LiuDepartment of Tropical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.
Jun LiDepartment of Infectious Disease, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chuanlong ZhuDepartment of Tropical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acute-on-chronic liver failureend stage liver diseasegranulocyte colony-stimulating factorhepatic insufficiencyrandomized controlled trial

Identifiers

PMID34869505
PMCPMC8635095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.