Evidence map›Paper›PMID 34869425›Full record

ArticleFrontiers in medicine2021

Hyperoxia Provokes Time- and Dose-Dependent Gut Injury and Endotoxemia and Alters Gut Microbiome and Transcriptome in Mice.

Yunhang Li, Yuanfa Tao, Jingyu Xu, Yihuai He, Wen Zhang, Zhigang Jiang, Ying He, Houmei Liu, Miao Chen, Wei Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Power and poison: The intersections of HThe Journal of biological chemistry · 2025
    Review
  4. Article
  5. Article
  6. Hyperoxia as a driver of gut dysbiosis.Frontiers in microbiology · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Impact of hyperoxia on the gut during critical illnesses.Critical care (London, England) · 2024
    Review
  12. Article
  13. Article
  14. Molecular Mechanisms of Hyperoxia-Induced Neonatal Intestinal Injury.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Optimizing POCritical care (London, England) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yunhang LiDepartment of Cardiology, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Yuanfa TaoDepartment of General Surgery, Renmin Hospital of Wuhan University, Wuhan, China.
Jingyu XuDepartment of Gastroenterology, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Yihuai HeDepartment of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Wen ZhangDepartment of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhigang JiangDepartment of Statistics, Zunyi Medical University, Zunyi, China.
Ying HeDepartment of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Houmei LiuDepartment of Endodontics, Affiliated Stomatological Hospital of Zunyi Medical University, Zunyi, China.
Miao ChenDepartment of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Wei ZhangDepartment of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zhouxiong XingDepartment of Critical Care Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Zunyi Medical University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Enterobacteriaceaegut injurygut microbiomehyperoxiainnate immunityNODoxygen therapytoll-like receptor-4

Identifiers

PMID34869425
PMCPMC8635731
OpenAlexW3213636668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.