ReviewFrontiers in medicine2021
Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis With Severe Ocular Complications.
Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Crosstalk mediators implicated in the Stevens-Johnson Syndrome through gene regulatory network analysis.BMC medical genomics · 2026Article
- A Systematic Review of Literature: TNF-α Blockers and JAK Inhibitors for the Treatment of Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Severe Forms of Erythema Multiforme.Health science reports · 2026Review
- Paradoxical Hemophagocytic Lymphohistiocytosis to Stevens-Johnson Syndrome - Toxic Epidermal Necrolysis- A rare immune phenomenon.Journal of postgraduate medicine · 2026Article
- RUCAM-ascertained immunology and autoimmunity specifics of six idiosyncratic drug-induced liver injury types with refined classification: their individual complex molecular interplay.Frontiers in immunology · 2026Review
- The Gut Microbiome in Stevens-Johnson Syndrome and Sjögren's Disease: Correlations with Dry Eye.Microorganisms · 2025Article
- Stevens-Johnson syndrome associated with daclatasvir and sofosbuvir co-therapy in hepatitis C treatment: a rare case report.Annals of medicine and surgery (2012) · 2025Article
- Liver Injury in Immune Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: Five New Classification Types.Journal of clinical and translational hepatology · 2025Review
- Anterior Segment Swept-Source Optical Coherence Tomography-based Assessment of Corneal Refractive Profiles in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Patients: A Controlled Comparative Study.Korean journal of ophthalmology : KJO · 2025Article
- Regulation of innate immune response by miRNAs up-regulated in Stevens-Johnson syndrome with severe ocular complications.Scientific reports · 2025Article
- HLA B*15:02 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: first case report from Nepal with genetic analysis.Annals of medicine and surgery (2012) · 2025Article
- Ophthalmic Aspects of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Narrative Review.Ophthalmology and therapy · 2023Review
- Symblepharon in kittens: a retrospective study of 40 kittens and 54 eyes (2002-2022).Journal of feline medicine and surgery · 2023Article
- Chemotherapy-induced toxic epidermal necrolysis in a patient with multiple myeloma, a case report and literature review.Frontiers in oncology · 2023Article
- Severe ocular complications of SJS/TEN and associations among pre-onset, acute, and chronic factors: a report from the international ophthalmology collaborative group.Frontiers in medicine · 2023Article
- Susceptibility Genes and HLA for Cold Medicine-Related SJS/TEN with SOC.Frontiers in genetics · 2022Review
- Steven-Jonhson Syndrome in a Patient With Dengue Infection in Peru: A Case Report.Journal of investigative medicine high impact case reportsArticle
- Surgery for Symblepharon Developed Due to Stevens-Johnson Syndrome: Modified Ring Procedure Performed Through Amniotic Membrane Transplantation and a 6 French Aspiration Catheter.Romanian journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) is an acute inflammatory vesiculobullous reaction of the mucosa of the ocular surface, oral cavity, and genitals, and of the skin. Severe ocular complications (SOC) are observed in about half of SJS/TEN patients diagnosed by dermatologists and in burn units. Ophthalmologists treat SOC, and they tend to encounter the patients not only in the acute stage, but also in the chronic stage. Our investigation of the pathogenesis of SJS/TEN with SOC led us to suspect that abnormal innate mucosal immunity contributes to the ocular surface inflammation seen in SJS/TEN with SOC. We confirmed that cold medicines such as NSAIDs and multi-ingredient cold medications are the main causative drugs for SJS/TEN with SOC. Single nucleotide polymorphism (SNP) association analysis of cold medicine-related SJS/TEN with SOC showed that the Toll-like receptor 3 (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.