Evidence map›Paper›PMID 34869383›Full record

ArticleFrontiers in cell and developmental biology2021

Transmembrane Protein Ttyh1 Maintains the Quiescence of Neural Stem Cells Through Ca

Yuan Cao, Hai-Ning Wu, Xiu-Li Cao, Kang-Yi Yue, Wen-Juan Han, Zi-Peng Cao, Yu-Fei Zhang, Xiang-Yu Gao, Ceng Luo, Xiao-Fan Jiang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Yuan CaoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Hai-Ning WuState Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China.
Xiu-Li CaoDepartment of Medical Genetics and Developmental Biology, Fourth Military Medical University, Xi'an, China.
Kang-Yi YueDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wen-Juan HanDepartment of Neurobiology, Fourth Military Medical University, Xi'an, China.
Zi-Peng CaoDepartment of Occupational and Environmental Health, Fourth Military Medical University, Xi'an, China.
Yu-Fei ZhangState Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China.
Xiang-Yu GaoDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Ceng LuoDepartment of Neurobiology, Fourth Military Medical University, Xi'an, China.
Xiao-Fan JiangDepartment of Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Hua HanState Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China.
Min-Hua ZhengDepartment of Medical Genetics and Developmental Biology, Fourth Military Medical University, Xi'an, China.
Air Force Medical University · CNXijing Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quiescence, activation, and subsequent neurogenesis of neural stem cells (NSCs) play essential roles in the physiological homeostasis and pathological repair of the central nervous system. Previous studies indicate that transmembrane protein Ttyh1 is required for the stemness of NSCs, whereas the exact functions

Indexed as

neural stem cellneurogenesisquiescencestemnessTtyh1

Identifiers

PMID34869383
PMCPMC8635056
OpenAlexW3214126968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.