Evidence map›Paper›PMID 34869276›Full record

ArticleFrontiers in bioengineering and biotechnology2021

A Three-Dimensional Co-Culture Model for Rheumatoid Arthritis Pannus Tissue.

Jietao Lin, Antonia RuJia Sun, Jian Li, Tianying Yuan, Wenxiang Cheng, Liqing Ke, Jianhai Chen, Wei Sun, Shengli Mi, Peng Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Mechanistic Study of Yibi Decoction in Treating Rheumatoid ArthritisEndocrine, metabolic & immune disorders drug targets · 2026
    Article
  3. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
  4. Review
  5. Review
  6. Emerging Landscape ofACS pharmacology & translational science · 2024
    Review
  7. Article
  8. Mimicking the Human Articular Joint withInternational journal of stem cells · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Jietao LinCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Antonia RuJia SunCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Jian LiCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Tianying YuanBiomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Wenxiang ChengCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Liqing KeCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Jianhai ChenCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Wei SunBiomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Shengli MiBiomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing, China.
Peng ZhangCenter for Translational Medicine Research and Development, Shenzhen Institute of Advanced Technology, Chinese Academy of Science, Shenzhen, China.
Shenzhen Institutes of Advanced Technology · CNTsinghua University · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) co-culture models have closer physiological cell composition and behavior than traditional 2D culture. They exhibit pharmacological effects like

Indexed as

3D bioprintingdrug screeningpannus tissue modelrheumatoid arthritistissue engineering

Identifiers

PMID34869276
PMCPMC8638776
OpenAlexW3211841284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.