Evidence map›Paper›PMID 34868981›Full record

ArticleFrontiers in oncology2021

Lin28A/CENPE Promoting the Proliferation and Chemoresistance of Acute Myeloid Leukemia.

Mingyue Shi, Junwei Niu, Xiaona Niu, Honggang Guo, Yanliang Bai, Jie Shi, Weiya Li, Kai Sun, Yuqing Chen, Fengmin Shao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mingyue ShiDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Junwei NiuDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Xiaona NiuDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Honggang GuoDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Yanliang BaiDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Jie ShiDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Weiya LiDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Kai SunDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Yuqing ChenDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Fengmin ShaoDepartment of Nephrology, Henan Provincial Key Laboratory of Kidney Disease and Immunology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou, China.
Henan Provincial People's Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of chemoresistant acute myeloid leukemia (AML) is still poor, mainly owing to the sustained proliferation ability of leukemic cells, while the microtubules have a major role in sustaining the continuity of cell cycle. In the present study, we have identified CENPE, a microtubular kinesin-like motor protein that is highly expressed in the peripheral blood of patients with chemoresistant AML. In our

Indexed as

AMLcell cycleCENPEchemoresistanceLIN28A

Identifiers

PMID34868981
PMCPMC8632764
OpenAlexW3212918164

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.