Evidence map›Paper›PMID 34868975›Full record

ReviewFrontiers in oncology2021

Ultrasound-Guided Thermal Ablation of Thyroid Nodules: Technicalities Progress and Clinical Applications, Especially in Malignant Thyroid Nodules.

Enock Adjei Agyekum, Jian-Hua Fu, Fei-Ju Xu, Yong-Zhen Ren, Debora Akortia, Qing Chen, Xiao-Qin Qian, Yuguo Wang, Xian Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Current evidence and strategies for preventing tumor recurrence following thermal ablation of papillary thyroid carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Enock Adjei AgyekumDepartment of Ultrasound, Jiangsu University Affiliated People's Hospital, Zhenjiang, China.
Jian-Hua FuDepartment of Interventional Radiology, Jiangsu University Affiliated People's Hospital, Zhenjiang, China.
Fei-Ju XuDepartment of Ultrasound, Jiangsu University Affiliated People's Hospital, Zhenjiang, China.
Yong-Zhen RenSchool of Medicine, Jiangsu University, Zhenjiang, China.
Debora AkortiaSchool of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Qing ChenDepartment of Ultrasound, Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing, China.
Xiao-Qin QianDepartment of Ultrasound, Jiangsu University Affiliated People's Hospital, Zhenjiang, China.
Yuguo WangDepartment of Ultrasound, Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing, China.
Xian WangDepartment of Ultrasound, Jiangsu University Affiliated People's Hospital, Zhenjiang, China.
Jiangsu University · CNAffiliated Hospital of Jiangsu University · CNNanjing Traditional Chinese Medicine Hospital · CNKwame Nkrumah University of Science and Technology · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid nodules are commonly encountered in health care practice. They are usually benign in nature, with few cases being malignant, and their detection has increased in the adult population with the help of ultrasonography. Thyroidectomy or surgery is the first-line treatment and traditional method for thyroid nodules; however, thyroidectomy leaves permanent scars and requires long-term use of levothyroxine after surgery, which makes patients more reticent to accept this treatment. Thermal ablation is a minimally-invasive technique that have been employed in the treatment of benign and malignant thyroid nodules nodules, and have been shown to be effective and safe. Several studies, including long-term, retrospective, and prospective studies, have investigated the use of ablation to treat benign thyroid nodules and malignant thyroid nodules, including papillary thyroid carcinoma. Here, we review the recent progress in thermal ablation techniques for treating benign and malignant nodules, including their technicalities, clinical applications, pitfalls and limitations, and factors that could affect treatment outcomes. Special in-depth elaboration on the recent progress of the application of thermal ablation therapy in malignant thyroid nodules.

Indexed as

thermal ablationthyroid carcinomathyroidectomythyroid noduleultrasonography

Identifiers

PMID34868975
PMCPMC8637803
OpenAlexW3213594939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.