Evidence map›Paper›PMID 34868971›Full record

ArticleFrontiers in oncology2021

The Evolving Strategy of Californium-252 Neutron Intracavitary Brachytherapy in Treating Patients With Low-Lying T2 or T3 Rectal Adenocarcinoma: From Fixed to Individualized Regime With Intrarectal Peritumoral Injection of Amifostine.

Yanli Xiong, Li Shao, Jia Liu, Qian Zhou, Chongyi Li, Maojun Liao, Lei Zhang, Xiaoyan Dai, Mengxia Li, Xin Lei

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yanli XiongCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Li ShaoZhong Ke Pu Rui (ZKPR) Neutron Brachytherapy Center, Daping Hospital, Army Medical University, Chongqing, China.
Jia LiuZhong Ke Pu Rui (ZKPR) Neutron Brachytherapy Center, Daping Hospital, Army Medical University, Chongqing, China.
Qian ZhouCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Chongyi LiCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Maojun LiaoCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Lei ZhangCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Xiaoyan DaiCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Mengxia LiCancer Center, Daping Hospital, Army Medical University, Chongqing, China.
Xin LeiCancer Center, Daping Hospital, Army Medical University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo retrospectively and comparatively evaluate the improvement of the efficacy and safety on the addition of

methodsPhase I: from 2009 to 2011, 157 patients were treated with additional

resultsThe 4-year local control rates for the entire T2 and T3 patients were 69.4, 72.0, and 79.3%, while the 4-year overall survival rates were 63.1, 54.7, and 72.0% (P=0.08), and the 4-year disease-free survival rates were 55.4, 52.0, and 69.5% (P=0.053) in Phases I, II, and III, respectively. The late complication (LAC, ≥G2) rates were 33.8, 26.7, and 15.9%, respectively (P=0.012), and the serious LAC (≥G3) rates were 4.5, 4.2, and 0%, respectively, in Phases I, II, and III.

conclusionConcurrent chemo-EBRT combined with individualized

Indexed as

252Cf neutronbrachytherapyradiotherapyrectal adenocarcinomasphincter preservation

Identifiers

PMID34868971
PMCPMC8636320

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.