Evidence map›Paper›PMID 34868687›Full record

ArticleProstate cancer2021

Cosmetic Appeal, HRQoL, and Effectiveness of Simple and Pseudotesticular Techniques of Orchidectomy in Prostate Cancer.

Ijeoma N C Chibuzo, Augustine O Takure, Olayiwola B Shittu, Linus I Okeke

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Prostate cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03744494 (Comparison of the Therapeutic Efficacy and Patient Satisfaction of Three Techniques of Bilateral Orchidectomy in Prostate Cancer Patients of a Nigerian Sub-population), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03744494 nacompletednot on this map

Comparison of the Therapeutic Efficacy and Patient Satisfaction of Three Techniques of Bilateral Orchidectomy in Prostate Cancer Patients of a Nigerian Sub-population (TEPSO)

TypeinterventionalSponsorUniversity College Hospital, IbadanRan2016 to 2018Enrolled63ConditionsProstate Cancer, Quality of Life, OrchiectomyArmsBilateral simple orchidectomy (BSO), Bilateral Subcapsular Orchidectomy, Bilateral Epididymal-sparing Orchidectomy
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ijeoma N C ChibuzoDepartment of Surgery, University College Hospital, Ibadan, Oyo State, Nigeria.ORCID https://orcid.org/0000-0002-8786-2505
Augustine O TakureDepartment of Surgery, University College Hospital, Ibadan, Oyo State, Nigeria.ORCID https://orcid.org/0000-0002-1557-8310
Olayiwola B ShittuDepartment of Surgery, University College Hospital, Ibadan, Oyo State, Nigeria.ORCID https://orcid.org/0000-0001-8179-5981
Linus I OkekeDepartment of Surgery, University College Hospital, Ibadan, Oyo State, Nigeria.ORCID https://orcid.org/0000-0003-3601-6365
University of Ibadan · NGUniversity College Hospital, Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOrchidectomy is the most cost-effective means of hormonal therapy for locally advanced or metastatic prostate cancer (LAMP). However, cost-effectiveness should not detract from health-related quality of life (HRQoL) considerations. Bilateral simple orchidectomy (BSO) has been linked to negative psychometric deficits from an empty scrotum. This study compared the HRQoL, therapeutic efficacy, and cosmetic appeal of BSO with endogenous pseudotesticular techniques of bilateral subcapsular orchidectomy (BSCO) and bilateral-epididymal-sparing orchidectomy (BESO).

resultSixty-three patients were recruited (24 BSO, 21 BSCO, 18 BESO), 73% of whom were low-income earners. There was no significant difference in the procedure cost nor the PSA or testosterone nadirs achieved over the three-month follow-up period (11.3, 12.6, 15.2 ng/ml (

conclusionEndogenous pseudotesticular techniques, when compared with BSO, reduce the negative psychological impact experienced by patients without increasing costs. BSCO produced the best pseudotesticular volumes and postoperative sexual function. This study is registered with the ClinicalTrials.gov of the National Institute of Health U.S. National Library of Medicine as TEPSO study, NCT03744494: Comparison of the Therapeutic Efficacy and Patient Satisfaction of Three Techniques of Bilateral Orchidectomy in Prostate Cancer Patients of a Nigerian Sub-population. Registration completed on 16

Identifiers

PMID34868687
PMCPMC8642020
OpenAlexW3216801483

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.