Evidence map›Paper›PMID 34868669›Full record

ArticleTranslational neuroscience2021

circ_0082375 promotes the progression of glioma by regulating Wnt7B.

Xianbing Meng, Hailong Tian, Wenqiang Guo, Zhigang Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Xianbing MengDepartment of Neurosurgery, Qilu Hospital of Shandong University, No. 758, Hefei Road, Shibei District, Qingdao City, Shandong Province, 266035, China.
Hailong TianDepartment of Neurosurgery, Qilu Hospital of Shandong University, No. 758, Hefei Road, Shibei District, Qingdao City, Shandong Province, 266035, China.
Wenqiang GuoDepartment of Neurosurgery, Qilu Hospital of Shandong University, No. 758, Hefei Road, Shibei District, Qingdao City, Shandong Province, 266035, China.
Zhigang WangDepartment of Neurosurgery, Qilu Hospital of Shandong University, No. 758, Hefei Road, Shibei District, Qingdao City, Shandong Province, 266035, China.
Qilu Hospital of Shandong University · CNShandong First Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs contribute to the progression of glioma. However, the biological role and underlying mechanism of circ_0082375 in glioma remain unclear. Quantitative real-time PCR and Western blot assay were used to evaluate the expression levels of circ_0082375, microRNA-485-5p, and Wnt family member 7B (Wnt7B). The overall survival of glioma patients was estimated by the Kaplan-Meier curve. Cell proliferation, apoptosis, invasion, and migration were detected by cell counting kit-8, 5-ethynyl-2 -deoxyuridine (EdU) staining, flow cytometry, and transwell assays, respectively. Glucose level and lactate production were determined using glucose and lactate assay kits.

Indexed as

circ_0082375gliomamiR-485-5pWnt7B

Identifiers

PMID34868669
PMCPMC8605768
OpenAlexW3216654563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.