ReviewEvidence-based complementary and alternative medicine : eCAM2021
Comparison of Herbal Agents with Sodium Hypochlorite as Root Canal Irrigant: A Systematic Review of
Review in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Efficacy of electronic apex locators in comparison with intraoral radiographs in working length determination- a systematic review and meta-analysis.BMC oral health · 2024Pooled it
- Antibiofilm efficacy of plant extracts as root canal irrigants in endodontics: a systematic literature review.Frontiers in dental medicine · 2024Pooled it
- Herbal Agents versus Ethylene Diamine Tetra Acetic Acid on Removal of the Smear Layer-A Systematic Review of In Vitro Studies.International journal of environmental research and public health · 2022Pooled it
- Antibacterial effect of chamomile extract irrigant activated with diode laser against Enterococcus faecalis.Lasers in medical science · 2026Article
- Assessing the Effectiveness of Herbal Intracanal Irrigants in Deciduous Molars: A Systematic Review.International journal of clinical pediatric dentistry · 2026Review
- Evaluation of Antimicrobial Efficacy of Different Root Canal Irrigants in Endodontic Treatment Cases: A Comparative Study.Journal of pharmacy & bioallied sciences · 2025Article
- Assessing the efficacy of frankincense extract as a root canal irrigant against Enterococcus faecalis.PloS one · 2025Article
- Comparative evaluation of the efficacy of 1% and 3% Sodium hypochlorite in reducing the microbial counts in primary teeth root canals using Bioluminometer - A randomized clinical trial.The Saudi dental journal · 2024Article
- Endodontic irrigants from a comprehensive perspective.World journal of clinical cases · 2024Review
- Effect of microbubble as local drug delivery system in endodontic management - AnThe Saudi dental journal · 2024Article
- Comparative Evaluation of Dental Pulp Tissue Dissolution Ability of Sapindus mukorossi and Sodium Hypochlorite.Cureus · 2024Article
- Comparative evaluation of antimicrobial efficacy of different combinations of calcium hydroxide against Enterococcus faecalis.BMC oral health · 2023Article
- Herbal Medications in Endodontics and Its Application-A Review of Literature.Materials (Basel, Switzerland) · 2022Review
- Article
- Influence of Commonly Used Endodontic Irrigants on the Setting Time and Metal Composition of Various Base Endodontic Sealers.Polymers · 2021Article
- Nano Drug Delivery Platforms for Dental Application: Infection Control and TMJ Management-A Review.Polymers · 2021Article
- Comparative Evaluation of Intracanal Smear Layer Removal by Different Root Canal Irrigants: A Scanning Electron Microscope Study.International journal of clinical pediatric dentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During endodontic treatment, eliminating microorganisms from the root canals should be considered with utmost importance. Before filling the canal, every effort should be made to ensure optimal shaping and adequate disinfection of the root canal system. This systematic review aimed to compare the efficacy of herbal agents with sodium hypochlorite (NaOCl) in reducing the microbial load while used as a root canal irrigant. The research question in the present study was to assess "Is there a significant difference in reducing microbial load comparing sodium hypochlorite (NaOCl) and herbal agents." Electronic databases (PubMed, Scopus, and Web of Science) were searched from their start dates to November 2020 using strict inclusion and exclusion criteria and reviewed following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Only
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.