Evidence map›Paper›PMID 34868080›Full record

ReviewFrontiers in immunology2021

The Chicken Embryo Model: A Novel and Relevant Model for Immune-Based Studies.

Paul Garcia, Yan Wang, Jean Viallet, Zuzana Macek Jilkova

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed.

  1. Gut microbes · 2026
    Review
  2. Article
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  9. Article
  10. Review
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  13. Review
  14. Review
  15. Frontiers in veterinary science · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Multi-parametric magnetic resonance imaging evaluation of a novelQuantitative imaging in medicine and surgery · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paul GarciaUniversité Grenoble Alpes, Grenoble, France.
Yan WangR&D Department, Inovotion, La Tronche, France.
Jean VialletR&D Department, Inovotion, La Tronche, France.
Zuzana Macek JilkovaUniversité Grenoble Alpes, Grenoble, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulation of the immune system is associated with many pathologies, including cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in biomedical research are rodents, and despite the various advantages they offer, their use also raises numerous drawbacks. Recently, another

Indexed as

AnimalsChick EmbryoChorioallantoic MembraneCytokinesGene Expression Regulation, DevelopmentalHumansImmune SystemInflammation MediatorsModels, AnimalReceptors, ImmunologicSignal TransductionSpecies SpecificityCytokinesInflammation MediatorsReceptors, Immunologicchick embryochickenchicken embryochorioallantoic membraneeggimmunologyontogenypreclinical model

Identifiers

PMID34868080
PMCPMC8640176

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.