Evidence map›Paper›PMID 34868049›Full record

ArticleFrontiers in immunology2021

Adoptive Transfer of Immune Cells Into RAG2IL-2Rγ-Deficient Mice During

Anna Wiszniewsky, Laura E Layland, Kathrin Arndts, Lisa M Wadephul, Ruth S E Tamadaho, Dennis Borrero-Wolff, Valerine C Chunda, Chi Anizette Kien, Achim Hoerauf, Samuel Wanji and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Comparative development of human filariaeFrontiers in tropical diseases · 2024
    Article
  5. Review
  6. Article
  7. Host genetic backgrounds: the key to determining parasite-host adaptation.Frontiers in cellular and infection microbiology · 2023
    Review
  8. Article
  9. ILC2s Control Microfilaremia DuringFrontiers in immunology · 2022
    Article
  10. NKp46Frontiers in immunology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Anna WiszniewskyInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Laura E LaylandInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Kathrin ArndtsInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Lisa M WadephulInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Ruth S E TamadahoInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Dennis Borrero-WolffInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Valerine C ChundaParasite and Vector Biology Research Unit, Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.
Chi Anizette KienParasite and Vector Biology Research Unit, Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.
Achim HoeraufInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
Samuel WanjiParasite and Vector Biology Research Unit, Department of Microbiology and Parasitology, Faculty of Science, University of Buea, Buea, Cameroon.
Manuel RitterInstitute for Medical Microbiology, Immunology and Parasitology (IMMIP), University Hospital Bonn (UKB), Bonn, Germany.
University Hospital Bonn · DEUniversity of Buea · CMGerman Center for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite long-term mass drug administration programmes, approximately 220 million people are still infected with filariae in endemic regions. Several research studies have characterized host immune responses but a major obstacle for research on human filariae has been the inability to obtain adult worms which in turn has hindered analysis on infection kinetics and immune signalling. Although the

Indexed as

Adoptive TransferAnimalsCytokinesDisease Models, AnimalDisease SusceptibilityDNA-Binding ProteinsFilariasisFilarioideaHost-Pathogen InteractionsInterleukin Receptor Common gamma SubunitMiceMice, KnockoutParasite LoadT-Lymphocyte SubsetsCytokinesDNA-Binding ProteinsInterleukin Receptor Common gamma SubunitRag2 protein, mouseadoptive transferanti-filarial immunityCD4+ and CD8+ T cellsFilariaeLitomosoides sigmodontisTh17 polarization

Identifiers

PMID34868049
PMCPMC8636703
OpenAlexW3216103427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.