Evidence map›Paper›PMID 34867997›Full record

ArticleFrontiers in immunology2021

Mutation in

Annesa Das, Kuldeep Singh Chauhan, Himanshu Kumar, Prafullakumar Tailor

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. CD8Frontiers in immunology · 2024
    Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Annesa DasLaboratory of Innate Immunity, National Institute of Immunology, New Delhi, India.
Kuldeep Singh ChauhanLaboratory of Innate Immunity, National Institute of Immunology, New Delhi, India.
Himanshu KumarDepartment of Biological Sciences, Laboratory of Immunology and Infectious Disease Biology, Indian Institute of Science Education and Research (IISER) Bhopal, Bhopal, India.
Prafullakumar TailorLaboratory of Innate Immunity, National Institute of Immunology, New Delhi, India.
National Institute of Immunology · INIndian Institute of Science Education and Research, Bhopal · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmacytoid dendritic cells (pDCs) are the key producers of type I interferons (IFNs), thus playing a central role in initiating antiviral immune response. Besides robust type I IFN production, pDCs also act as antigen presenting cells post immunogenic stimulation. Transcription factor

Indexed as

Mutation, MissensePoint MutationAnimalsBone NeoplasmsCell Line, TumorCpG IslandsDendritic CellsFemaleGene Expression RegulationHEK293 CellsHumansImmunity, InnateInterferon Regulatory Factor-8Interferon Regulatory FactorsInterferon Type IMaleInterferon Regulatory Factor-8Interferon Regulatory FactorsInterferon Type Iantiviral immune responseDC activationinnate immunityinterferon regulatory factor 8 (IRF8)interferon stimulated gene (ISG)IRF8R294Cplasmacytoid dendritic cells (pDCs)type I interferons (IFNs)

Identifiers

PMID34867997
PMCPMC8635750
OpenAlexW3212352582

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.