Evidence map›Paper›PMID 34867977›Full record

ArticleFrontiers in immunology2021

Complement-Mediated Differential Immune Response of Human Macrophages to

Gabriela W P Neves, Sarah Sze Wah Wong, Vishukumar Aimanianda, Catherine Simenel, J Iñaki Guijarro, Catriona Walls, Janet A Willment, Neil A R Gow, Carol A Munro, Gordon D Brown and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Silencing ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  4. Dectin-1 and dectin-2 drive protection againstFrontiers in immunology · 2025
    Article
  5. Article
  6. Silencing ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  7. Differential Recognition of Clinically RelevantJournal of fungi (Basel, Switzerland) · 2023
    Article
  8. Differential Recognition of Clinically RelevantJournal of fungi (Basel, Switzerland) · 2023
    Article
  9. Review
  10. Sporotrichosis Outbreak Due toJournal of fungi (Basel, Switzerland) · 2023
    Article
  11. Differential Recognition ofInfection and drug resistance · 2023
    Article
  12. Silencing ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  13. Current Models to Study theFrontiers in fungal biology · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Gabriela W P NevesCell Biology Department, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Sarah Sze Wah WongInstitut Pasteur, Molecular Mycology Unit, CNRS UMR2000, Paris, France.
Vishukumar AimaniandaInstitut Pasteur, Molecular Mycology Unit, CNRS UMR2000, Paris, France.
Catherine SimenelInstitut Pasteur, Biological NMR and HDX-MS Technological Platform, CNRS UMR3528, Paris, France.
J Iñaki GuijarroInstitut Pasteur, Biological NMR and HDX-MS Technological Platform, CNRS UMR3528, Paris, France.
Catriona WallsAberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Janet A WillmentAberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Neil A R GowAberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Carol A MunroAberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Gordon D BrownAberdeen Fungal Group, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.
Leila M Lopes-BezerraCell Biology Department, Rio de Janeiro State University, Rio de Janeiro, Brazil.
University of Aberdeen · GBCentre National de la Recherche Scientifique · FRUniversidade do Estado do Rio de Janeiro · BR

Funding

Medical Research Council MR/N006364/2Wellcome Trust 097377Wellcome Trust 101873Wellcome Trust 102705Wellcome Trust 102705/Z/13/ZWellcome Trust 200208Wellcome Trust 215599
6 · The paper itself

Abstract

In this study, the human immune response mechanisms against

Indexed as

SporothrixAntigens, FungalCell WallComplement ActivationComplement System ProteinsCytokinesGlycoproteinsHumansL-Lactate DehydrogenaseMacrophage-1 AntigenMacrophagesPathogen-Associated Molecular Pattern MoleculesPhagocytosisAntigens, FungalComplement System ProteinsCytokinesGlycoproteinsL-Lactate DehydrogenaseMacrophage-1 AntigenPathogen-Associated Molecular Pattern Moleculespeptido-rhamnomannancell wallcomplement receptor-3 (CR3)human macrophagesinnate immune responsepeptidorhamnomannan (PRM)Sporothrix brasiliensisSporothrix schenckii

Identifiers

PMID34867977
PMCPMC8636148
OpenAlexW3214539019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.