Evidence map›Paper›PMID 34867956›Full record

ArticleFrontiers in immunology2021

Therapeutic Potential of a Novel

Yunju Jeong, JooYeon Jhun, Seon-Yeong Lee, Hyun Sik Na, JeongWon Choi, Keun-Hyung Cho, Seung Yoon Lee, A Ram Lee, Sang-Jun Park, Hyun Ju You and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 42 citations in OpenAlex.

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  14. Frontiers in immunology · 2025
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  18. Immune network · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Yunju JeongDepartment of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Seoul, South Korea.
JooYeon JhunRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Seon-Yeong LeeRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Hyun Sik NaRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
JeongWon ChoiRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Keun-Hyung ChoRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Seung Yoon LeeRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
A Ram LeeRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Sang-Jun ParkResearch Center, BIFIDO Co., Ltd., Hongcheon, South Korea.
Hyun Ju YouInstitute of Environmental Health, School of Public Health, Seoul National University, Seoul, South Korea.
Ji-Won KimDivision of Rheumatology, Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, South Korea.
Myeong Soo ParkResearch Center, BIFIDO Co., Ltd., Hongcheon, South Korea.
Bin KwonResearch Center, BIFIDO Co., Ltd., Hongcheon, South Korea.
Mi-La ChoRheumatism Research Center, Catholic Research Institute of Medical Science, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Geun Eog JiDepartment of Food and Nutrition, Research Institute of Human Ecology, Seoul National University, Seoul, South Korea.
Sung-Hwan ParkDivision of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Catholic University of Korea · KRSeoul National University · KRThe Catholic University of Korea Seoul St. Mary's Hospital · KRDaegu Catholic University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potential therapeutic effects of probiotic bacteria in rheumatoid arthritis (RA) remain controversial. Thus, this study aimed to discover potential therapeutic bacteria based on the relationship between the gut microbiome and rheumatoid factor (RF) in RA. Bacterial genomic DNA was extracted from the fecal samples of 93 RA patients and 16 healthy subjects. Microbiota profiling was conducted through 16S rRNA sequencing and bioinformatics analyses. The effects of

Indexed as

AdultAnimalsArthritis, ExperimentalArthritis, RheumatoidBifidobacteriumBiodiversityCase-Control StudiesFemaleGastrointestinal MicrobiomeHumansIn Vitro TechniquesMaleMiceMice, Inbred DBAMice, Inbred NODMice, ObeseRheumatoid FactorBifidobacterium longummicrobiomerheumatoid arthritisrheumatoid factorT helper 17 cell

Identifiers

PMID34867956
PMCPMC8634832
OpenAlexW3211391423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.