Evidence map›Paper›PMID 34867874›Full record

ArticleFrontiers in microbiology2021

Putative Antimicrobial Peptides Within Bacterial Proteomes Affect Bacterial Predominance: A Network Analysis Perspective.

Anastasis Oulas, Margarita Zachariou, Christos T Chasapis, Marios Tomazou, Umer Z Ijaz, Georges Pierre Schmartz, George M Spyrou, Alexios Vlamis-Gardikas

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In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anastasis OulasBioinformatics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Margarita ZachariouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Christos T ChasapisNMR Center, Instrumental Analysis Laboratory, School of Natural Sciences, University of Patras, Patras, Greece.
Marios TomazouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Umer Z IjazSchool of Engineering, University of Glasgow, Glasgow, United Kingdom.
Georges Pierre SchmartzChair for Clinical Bioinformatics, Saarland University, Saarbrücken, Germany.
George M SpyrouBioinformatics Department, The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Alexios Vlamis-GardikasDivision of Organic Chemistry, Biochemistry and Natural Products, Department of Chemistry, University of Patras, Patras, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The predominance of bacterial taxa in the gut, was examined in view of the putative antimicrobial peptide sequences (AMPs) within their proteomes. The working assumption was that compatible bacteria would share homology and thus immunity to their putative AMPs, while competing taxa would have dissimilarities in their proteome-hidden AMPs. A network-based method ("Bacterial Wars") was developed to handle sequence similarities of predicted AMPs among

Indexed as

bacterial competitionbioinformatics analysisinterbacterial antagonismnetwork analysisputative antimicrobial peptides

Identifiers

PMID34867874
PMCPMC8636115

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.