Evidence map›Paper›PMID 34867801›Full record

ArticleFrontiers in endocrinology2021

Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.

He Jiang, Fei-Fei Yuan, Hai-Ning Wang, Wei Liu, Xiao-Ping Ye, Shao-Ying Yang, Hui-Jun Xie, Sha-Sha Yu, Yu-Ru Ma, Le-Le Zhang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Association ofFrontiers in microbiology · 2026
    Article
  2. Review
  3. Polymorphisms rs2074292 of theHealth science reports · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

He JiangLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Fei-Fei YuanLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Hai-Ning WangDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wei LiuDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiao-Ping YeDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shao-Ying YangDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hui-Jun XieDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Sha-Sha YuDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yu-Ru MaDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Le-Le ZhangDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shuang-Xia ZhaoDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huai-Dong SongDepartment of Molecular Diagnostic and Endocrinology, The Core Laboratory in Medical Center of Clinical Research, The Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
China Consortium for the Genetics of Autoimmune Thyroid Disease
Shanghai Jiao Tong University · CNShanghai Ninth People's Hospital · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in

Indexed as

Asian PeopleCD40 AntigensChromosomes, Human, Pair 20Cohort StudiesFemaleGraves DiseaseHumansMalePolymorphism, Single NucleotideCD40 Antigensassociation analysisCD40expression quantitative trait locusGraves’ diseasesingle nucleotide polymorphisms

Identifiers

PMID34867801
PMCPMC8639283
OpenAlexW3214574285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.