Evidence map›Paper›PMID 34867542›Full record

ArticleFrontiers in psychiatry2021

Neurofilament Light Chain Is a Promising Biomarker in Alcohol Dependence.

Yanfei Li, Ranran Duan, Zhe Gong, Lijun Jing, Tian Zhang, Yong Zhang, Yanjie Jia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

  1. Neurofilament Light Chain in Cerebrospinal Fluid and Blood Identifies Patients With Minimal and Overt Hepatic Encephalopathy.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  2. Article
  3. Article
  4. MAO-B status in alcohol use disorder: a [Molecular psychiatry · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yanfei LiDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Ranran DuanDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhe GongDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Lijun JingDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Tian ZhangDepartment of Rehabilitation, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yong ZhangDepartment of Magnetic Resonance Imaging, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yanjie JiaDepartment of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alcohol dependencebiomarkergray matter volumeneuropsychological assessmentNfLNLRP3white matter lesions

Identifiers

PMID34867542
PMCPMC8637455
OpenAlexW3213949083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.