Evidence map›Paper›PMID 34867530›Full record

ArticleFrontiers in psychiatry2021

Mitochondria-Related Nuclear Gene Expression in the Nucleus Accumbens and Blood Mitochondrial Copy Number After Developmental Fentanyl Exposure in Adolescent Male and Female C57BL/6 Mice.

Cali A Calarco, Megan E Fox, Saskia Van Terheyden, Makeda D Turner, Jason B Alipio, Ramesh Chandra, Mary Kay Lobo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Review
  8. Photo-affinity and Metabolic Labeling Probes Based on the Opioid Alkaloids.Chembiochem : a European journal of chemical biology · 2024
    Article
  9. Development disturbed: sex-specific transcriptional alterations in adolescent mice after perinatal fentanyl exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Cali A CalarcoDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Megan E FoxDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Saskia Van TerheydenDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Makeda D TurnerDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Jason B AlipioDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Ramesh ChandraDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
Mary Kay LoboDepartment of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States.
University of Maryland, Baltimore · US

Funding

Cocaine-induced mitochondrial mechanisms and molecular mediators in reward circuitryR01DA038613 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI LOBO, MARY KAY · 2014 to 2025
$4.9M
The neurocircuitry of depression: Molecular and Cell Subtype MechanismsR01MH106500 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI LOBO, MARY KAY · 2015 to 2024
$4.5M
Diabetes, Obesity, and Metabolic ComplicationsT32DK098107 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI TAYLOR, SIMEON I. · 2015 to 2025
$2.4M
Circuit-specific molecular mechanisms in fentanyl use and relapseR00DA050575 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI FOX, MEGAN ELIZABETH · 2022 to 2024
$747k
Circuit-specific molecular mechanisms in fentanyl use and relapseK99DA050575 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI FOX, MEGAN ELIZABETH · 2020 to 2021
$352k
Enduring effects in thalamocortical circuits ensuing perinatal opioid exposureF31DA051113 · NIDA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALIPIO, JASON BONDOC · 2021 to 2021
$32k
NIDA NIH HHS F31 DA051113NIDA NIH HHS K99 DA050575NIDA NIH HHS R00 DA050575NIDA NIH HHS R01 DA038613NIDDK NIH HHS T32 DK098107NIMH NIH HHS R01 MH106500
6 · The paper itself

Abstract

The potency of the synthetic opioid fentanyl and its increased clinical availability has led to the rapid escalation of use in the general population, increased recreational exposure, and subsequently opioid-related overdoses. The wide-spread use of fentanyl has, consequently, increased the incidence of

Indexed as

developmental drug exposurefentanylgene expressionmitochondriamitochondrial copy numbernucleus accumbens

Identifiers

PMID34867530
PMCPMC8637046
OpenAlexW3214687724

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.