Evidence map›Paper›PMID 34867460›Full record

ArticleFrontiers in physiology2021

Leukotriene D

Sabita Pokhrel, Ravindra Gudneppanavar, Lakshminarayan Reddy Teegala, Ernest Duah, Charles K Thodeti, Sailaja Paruchuri

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sabita PokhrelDepartment of Chemistry, University of Akron, Akron, OH, United States.
Ravindra GudneppanavarDepartment of Chemistry, University of Akron, Akron, OH, United States.
Lakshminarayan Reddy TeegalaDepartment of Chemistry, University of Akron, Akron, OH, United States.
Ernest DuahDepartment of Chemistry, University of Akron, Akron, OH, United States.
Charles K ThodetiDepartment of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, United States.
Sailaja ParuchuriDepartment of Chemistry, University of Akron, Akron, OH, United States.
University of Akron · USNortheast Ohio Medical University · USUniversity of Toledo · US

Funding

Mechanical Control of Coronary Angiogenesis in Myocardial Adaptation to IschemiaR01HL148585 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI THODETI, CHARLES K · 2019 to 2022
$1.8M
Integration of Leukotriene and Prostaglandin Receptor Signaling in Mast Cell Activation and Pulmonary Inflammation during AsthmaR01AI144115 · NIAID · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI PARUCHURI, SAILAJA · 2019 to 2023
$1.8M
NHLBI NIH HHS R01 HL148585NIAID NIH HHS R01 AI144115
6 · The paper itself

Abstract

Endothelial permeability, leukocyte attachment, and unregulated oxidized LDL (oxLDL) uptake by macrophages leading to the formation of foam cells are all vital in the initiation and progression of atherosclerosis. During inflammation, several inflammatory mediators regulate this process through the expression of distinct oxLDL binding cell surface receptors on macrophages. We have previously shown that Leukotriene D

Indexed as

atherosclerosisCD36CysLT1RLTD4MCP-1OLR1oxLDLphagocytosis

Identifiers

PMID34867460
PMCPMC8637273
OpenAlexW3214846244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.